临床合理用药杂志
臨床閤理用藥雜誌
림상합리용약잡지
CHINESE JOURNAL OF CLINICAL RATIONAL DRUG USE
2014年
28期
7-8
,共2页
王惠%刘振旭%王风光%王扎根
王惠%劉振旭%王風光%王扎根
왕혜%류진욱%왕풍광%왕찰근
阿奇霉素%头孢克肟%肺炎%小儿%临床效果%不良反应
阿奇黴素%頭孢剋肟%肺炎%小兒%臨床效果%不良反應
아기매소%두포극우%폐염%소인%림상효과%불량반응
Azithromycin%Cefixime%Pneumonia%Children%Clinical effect%Adverse reactions
目的:观察阿奇霉素辅治小儿肺炎的临床效果及不良反应,为治疗小儿肺炎提供可靠依据。方法将66例肺炎患儿随机分成试验组和对照组各33例,对照组患者给予头孢克肟颗粒口服,试验组在对照组基础上给予阿奇霉素颗粒口服,比较2组临床疗效、咳嗽消除用时、体温恢复用时、肺组织啰音消除用时、住院时长,以及不良反应发生率。结果试验组总有效率为93.9%高于对照组的75.8%( P<0.05);试验组患儿的咳嗽消除用时、体温恢复用时、肺组织啰音消除用时、住院时长均短于对照组( P<0.05);试验组患儿的不良反应发生率低于对照组( P<0.05)。结论阿奇霉素辅治小儿肺炎的疗效明显、改善症状用时少,显著缩短了治疗时间,减少了不良反应发生率,对小儿肺炎治疗意义较大,值得临床推广。
目的:觀察阿奇黴素輔治小兒肺炎的臨床效果及不良反應,為治療小兒肺炎提供可靠依據。方法將66例肺炎患兒隨機分成試驗組和對照組各33例,對照組患者給予頭孢剋肟顆粒口服,試驗組在對照組基礎上給予阿奇黴素顆粒口服,比較2組臨床療效、咳嗽消除用時、體溫恢複用時、肺組織啰音消除用時、住院時長,以及不良反應髮生率。結果試驗組總有效率為93.9%高于對照組的75.8%( P<0.05);試驗組患兒的咳嗽消除用時、體溫恢複用時、肺組織啰音消除用時、住院時長均短于對照組( P<0.05);試驗組患兒的不良反應髮生率低于對照組( P<0.05)。結論阿奇黴素輔治小兒肺炎的療效明顯、改善癥狀用時少,顯著縮短瞭治療時間,減少瞭不良反應髮生率,對小兒肺炎治療意義較大,值得臨床推廣。
목적:관찰아기매소보치소인폐염적림상효과급불량반응,위치료소인폐염제공가고의거。방법장66례폐염환인수궤분성시험조화대조조각33례,대조조환자급여두포극우과립구복,시험조재대조조기출상급여아기매소과립구복,비교2조림상료효、해수소제용시、체온회복용시、폐조직라음소제용시、주원시장,이급불량반응발생솔。결과시험조총유효솔위93.9%고우대조조적75.8%( P<0.05);시험조환인적해수소제용시、체온회복용시、폐조직라음소제용시、주원시장균단우대조조( P<0.05);시험조환인적불량반응발생솔저우대조조( P<0.05)。결론아기매소보치소인폐염적료효명현、개선증상용시소,현저축단료치료시간,감소료불량반응발생솔,대소인폐염치료의의교대,치득림상추엄。
Objective To observe the clinical effect and adverse reactions observation of Azithromycin in children with pneumonia .Methods 66 cases children with pneumonia were randomly divided into test group and control group ,each of 33 cases.Control group was treated by Cefixime .Test group,on the basis of control group,was treated by Azithromycin.After treatment,compared the clinical effect ,the cough disappeared time ,the temperature recovery time ,the lung tissue rales disap-peared time,the hospital stay and the incidence of adverse reactions of 2 groups.Results The total efficacy of test group (93.9%)was higher than that of control group (75.8%),the difference was statistically sifnificant (P<0.05).The cough dis-appeared time ,the temperature recovery time ,the lung tissue rales disappeared time ,the hospital stay of test group was shorter than that of control group,the difference was statistically significant(P<0.05).The adverse reactions of test group was lower than that of control group,the difference was statistically significant (P<0.05).Conclusion Azithromycin in children with pneumonia has an good effect ,shorten the operative time ,has an important significant .