中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2014年
27期
25-26
,共2页
血小板%血小板抗体%交叉配型%CCI
血小闆%血小闆抗體%交扠配型%CCI
혈소판%혈소판항체%교차배형%CCI
Platelet%Platelet antibody%Crossmatch%CCI
目的：探讨血小板抗体筛选及血小板交叉配型在临床的应用及其对血小板输注效果的影响，为临床合理用血提供参考。方法：选择384例临床输注血小板患者，随机分为对照组及研究组，对照组给予常规方法输注血小板，研究组患者输注前检测血小板抗体，抗体阴性患者给予常规输注血小板，血小板抗体阳性患者给予血小板交叉配型后输注血小板，比较两组患者血小板输注临床效果。结果：对照组患者输注有效率为91.4%，研究组输注有效率为95.5%，两组患者输注有效率比较差异无统计学意义(P>0.05)，研究组输注后1 h及24 h CCI为9.6±1.8和7.2±1.6，对照组输注后1 h及24 h CCI为8.9±1.9和6.1±1.4，研究组输注后1 h及24 h CCI高于对照组(P<0.05)。结论：血小板输注前常规进行血小板抗体筛选，血小板抗体阳性患者进行交叉配型能够改善血小板输注效果。
目的：探討血小闆抗體篩選及血小闆交扠配型在臨床的應用及其對血小闆輸註效果的影響，為臨床閤理用血提供參攷。方法：選擇384例臨床輸註血小闆患者，隨機分為對照組及研究組，對照組給予常規方法輸註血小闆，研究組患者輸註前檢測血小闆抗體，抗體陰性患者給予常規輸註血小闆，血小闆抗體暘性患者給予血小闆交扠配型後輸註血小闆，比較兩組患者血小闆輸註臨床效果。結果：對照組患者輸註有效率為91.4%，研究組輸註有效率為95.5%，兩組患者輸註有效率比較差異無統計學意義(P>0.05)，研究組輸註後1 h及24 h CCI為9.6±1.8和7.2±1.6，對照組輸註後1 h及24 h CCI為8.9±1.9和6.1±1.4，研究組輸註後1 h及24 h CCI高于對照組(P<0.05)。結論：血小闆輸註前常規進行血小闆抗體篩選，血小闆抗體暘性患者進行交扠配型能夠改善血小闆輸註效果。
목적：탐토혈소판항체사선급혈소판교차배형재림상적응용급기대혈소판수주효과적영향，위림상합리용혈제공삼고。방법：선택384례림상수주혈소판환자，수궤분위대조조급연구조，대조조급여상규방법수주혈소판，연구조환자수주전검측혈소판항체，항체음성환자급여상규수주혈소판，혈소판항체양성환자급여혈소판교차배형후수주혈소판，비교량조환자혈소판수주림상효과。결과：대조조환자수주유효솔위91.4%，연구조수주유효솔위95.5%，량조환자수주유효솔비교차이무통계학의의(P>0.05)，연구조수주후1 h급24 h CCI위9.6±1.8화7.2±1.6，대조조수주후1 h급24 h CCI위8.9±1.9화6.1±1.4，연구조수주후1 h급24 h CCI고우대조조(P<0.05)。결론：혈소판수주전상규진행혈소판항체사선，혈소판항체양성환자진행교차배형능구개선혈소판수주효과。
Objective:To investigate the application and effect of platelet crossmatch and platelet antibody screening for platelet transfusion,and provide reference for reasonable use of blood in clinic.Method:384 cases of patients who transfuse platelet were selected and randomly divided into research group and control group,platelet in the control group were transfused with common ways,and platelet antibody was detecting before platelet transfusion in research group, and platelet were transfused with common ways in patients with negative antibody,and platelet were transfused after crossmatch in patients with positive antibody, and transfuse effect were contrasted between research group and control group.Result:Effective rate of platelet transfusion was 91.4% in control group and was 95.5% in research group,effect rate in two groups had no significant difference(P>0.05),and CCI at 1 hour and 24 hours after transfusion was 9.6±1.8 and 7.2±1.6 in research group,CCI at 1 hour and 24 hours after transfusion was 8.9±1.9 and 6.1±1.4 in control group,CCI at 1 hour and 24 hours after transfusion was higher in research groups than those in control group(P<0.05).Conclusion:Platelet antibody screening should be taken before platelet transfusion and platelet crossmatch in patients with positive antibody,it can improve effect of platelet transfusion.
