国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2014年
1期
90-92
,共3页
乙型肝炎%复发%HBV-DNA%相关性
乙型肝炎%複髮%HBV-DNA%相關性
을형간염%복발%HBV-DNA%상관성
Hepatitis B (HB)%Recurrence%HBV-DNA%Correlation
目的 探讨乙型肝炎(HB)核苷类药物治疗停药后复发与血清HBV-DNA水平的相关性.方法 选取180例2010年5月至2012年5月在我院门诊接受核苷类药物阿德福韦酯治疗的HB患者.检测患者治疗前及治疗4w后血清HBV-DNA水平.结果 HBeAg(+)时,患者停药后复发与血清HBV-DNA水平密切相关.HBeAg(-)时,患者停药后复发和血清HBV-DNA水平同样密切相关.结论 HB患者抗病毒治疗停药后复发和患者治疗前的血清HBV-DNA水平、治疗早期HBV-DNA水平及血清HBV-DNA水平降幅存在相关性.
目的 探討乙型肝炎(HB)覈苷類藥物治療停藥後複髮與血清HBV-DNA水平的相關性.方法 選取180例2010年5月至2012年5月在我院門診接受覈苷類藥物阿德福韋酯治療的HB患者.檢測患者治療前及治療4w後血清HBV-DNA水平.結果 HBeAg(+)時,患者停藥後複髮與血清HBV-DNA水平密切相關.HBeAg(-)時,患者停藥後複髮和血清HBV-DNA水平同樣密切相關.結論 HB患者抗病毒治療停藥後複髮和患者治療前的血清HBV-DNA水平、治療早期HBV-DNA水平及血清HBV-DNA水平降幅存在相關性.
목적 탐토을형간염(HB)핵감류약물치료정약후복발여혈청HBV-DNA수평적상관성.방법 선취180례2010년5월지2012년5월재아원문진접수핵감류약물아덕복위지치료적HB환자.검측환자치료전급치료4w후혈청HBV-DNA수평.결과 HBeAg(+)시,환자정약후복발여혈청HBV-DNA수평밀절상관.HBeAg(-)시,환자정약후복발화혈청HBV-DNA수평동양밀절상관.결론 HB환자항병독치료정약후복발화환자치료전적혈청HBV-DNA수평、치료조기HBV-DNA수평급혈청HBV-DNA수평강폭존재상관성.
Objective To research the relativity analysis between recurrence after antiviral treatment of hepatitis B (HB) stopped and serum HBV-DNA level.Methods 180 HB outpatients treated with Adefovir Dipivoxil were selected from May 2010 to May 2012 in our hospital.The serum HBV DNA levels of the patients were detected before treatment and 4 weeks after treatment.Results As HBeAg (+),patients' relapse after drug withdrawal was closely related to serum HBV-DNA level.As HBeAg (-),patients' relapse after drug withdrawal was also closely related to serum HBV-DNA level.Conclusion HB recurrence after discontinuation of antiviral therapy in patients was correlated with the serum HBV-DNA levels before treatment,early HBV-DNA level after treatment and decreasing amplitude of the serum HBV-DNA levels after treatment.
