CAJ | 학술논문

目的：研究不同年龄段肾癌患者的临床特点，以提高肾癌诊治水平。方法回顾分析山东大学附属省立医院泌尿微创中心自2003年7月到2013年6月收治的107例青年（≤44岁）、156例中年（45～59岁）、141例老年（≥60岁）肾癌患者的临床资料并进行对比。结果性别比例、腰痛比例、透明细胞癌比例及平均瘤体最大径在三组间呈梯度变化，但无统计学意义（P＞0．05）；而各组嫌色细胞癌比例差异明显（P＜0．05）；偶发患者比例、瘤体大于7cm的比例在青年组与老年组差异显著（P＜0．05）；随访3～122月，三组无瘤生存率差别不大。结论青年、中年、老年肾癌患者临床特点有区别。嫌色细胞癌发病率随年龄增高而减低；青年患者更易出现血尿、腰痛等临床症状，而通过健康查体等途径发现的无症状肾癌多见于老年组；青年组瘤体大于7cm的明显多于老年组。
목적：연구불동년령단신암환자적림상특점，이제고신암진치수평。방법회고분석산동대학부속성립의원비뇨미창중심자2003년7월도2013년6월수치적107례청년（≤44세）、156례중년（45～59세）、141례노년（≥60세）신암환자적림상자료병진행대비。결과성별비례、요통비례、투명세포암비례급평균류체최대경재삼조간정제도변화，단무통계학의의（P＞0．05）；이각조혐색세포암비례차이명현（P＜0．05）；우발환자비례、류체대우7cm적비례재청년조여노년조차이현저（P＜0．05）；수방3～122월，삼조무류생존솔차별불대。결론청년、중년、노년신암환자림상특점유구별。혐색세포암발병솔수년령증고이감저；청년환자경역출현혈뇨、요통등림상증상，이통과건강사체등도경발현적무증상신암다견우노년조；청년조류체대우7cm적명현다우노년조。
Objective To study the clinical characteristics of RCC patients in different ages and improve the diagnosis and treatment of kidney cancer .Methods A retrospective analysis was performed with clinical data of 404 patients from July 2003 to June 2013 in Shandong Provincial Hospital Affiliated to Shandong University . They were divided into the young (≤44 years old),the mid-aged(45~59 years old) and the old group(≥60 years old) which respectively containing 107,156 and 141cases.Results Sex ratio, proportion of low back pain, incidence of ccRCC , and average maximum-diameter among three groups show a gradient trend , but not statis-tically significant(P>0.05).The incidences of chromophobe RCC significantly differs between groups (P<0.05);while incidental patients, tumors larger than 7cm are more in the young than in the old group (P<0.05).After 3~122 months of follow-up, cancer-free survivals of groups are similar .Conclusion RCC pa-tients in different ages have discriminate clinical feature .Incidence of chRCC increases with age decreasing . Youth are more likely to show hematuria , low back pain and other clinical symptoms; while incidental RCC is common in elderly patients .Besides , the ratio of tumor-diameter≥7 cm in young patients are obviously more than in the old .