CAJ | 학술논문

目的：比较不同剂量黄体酮对习惯性早期流产患者的临床效果。方法50例习惯性早期流产患者按照黄体酮用药剂量不同分为大剂量组和小剂量组各25例，所有患者连续治疗2个月后进行相关指标统计，并比较差异性。结果大剂量组体内血清HCG平均值为22199±208 IU/L，E2平均值1098±75 pmol/L，P平均值135±27 nmol/L，明显高于小剂量组统计结果（P<0.05），保胎治疗结束后，大剂量组保胎成功率为96%（24/25），明显高于小剂量组（P<0.05）。结论40mg剂量黄体酮在治疗习惯性早期流产方面具有较高的疗效和安全性。
목적：비교불동제량황체동대습관성조기유산환자적림상효과。방법50례습관성조기유산환자안조황체동용약제량불동분위대제량조화소제량조각25례，소유환자련속치료2개월후진행상관지표통계，병비교차이성。결과대제량조체내혈청HCG평균치위22199±208 IU/L，E2평균치1098±75 pmol/L，P평균치135±27 nmol/L，명현고우소제량조통계결과（P<0.05），보태치료결속후，대제량조보태성공솔위96%（24/25），명현고우소제량조（P<0.05）。결론40mg제량황체동재치료습관성조기유산방면구유교고적료효화안전성。
Objective To compare different doses of progesterone in patients with early habitual abortion results. Methods 50 cases of patients with early abortion in accordance with the cus-tomary dose of progesterone were divided into high-dose group and low dose group with 25 cases, all consecutive patients with therapy-related statistical indicators in February after and compare the difference. Results High-dose group the serum HCG average of 22199±208IU/L,E2 average of 1098±75pmol/L,P average of 135±27nmol/L,significantly higher than the low-dose group statisti-cal results(P<0.05) after the end of the miscarriage treatment, high-dose group miscarriage success rate was 96%(24/25), significantly higher than the low-dose group (P<0.05). Conclusion 40mg dose of progesterone had a high efficacy and safety in the treatment of habitual aspects of early habitual abortion.