CAJ | 학술논문

4H-色烯衍生物作为一种便宜易得的酸性无机盐，可有效催化Hantzsch 反应合成4H-色烯衍生物。在优化条件下，4 H-色烯衍生物可通过简单的过滤操作直接分离得到，含有催化剂的滤液则可以继续催化该反应，循环催化3次而不失活。这为4H-色烯衍生物的合成提供了一种实用且绿色化程度较高的方法，有潜在的工业化应用前景。
4H-색희연생물작위일충편의역득적산성무궤염，가유효최화Hantzsch 반응합성4H-색희연생물。재우화조건하，4 H-색희연생물가통과간단적과려조작직접분리득도，함유최화제적려액칙가이계속최화해반응，순배최화3차이불실활。저위4H-색희연생물적합성제공료일충실용차록색화정도교고적방법，유잠재적공업화응용전경。
4H-chromene derivatives could be efficiently synthesized via Hantzsch reaction catalyzed by potassium dihydrogen phosphate , which is an inexpensive acidic inorganic salt .Under the optimized conditions , 4H-chromene derivatives could be directly separated in high yields via simple filtration .The filtrate containing potassium dihydrogen phosphate could be directly reused to catalyze this reaction for three times without appreciable loss of catalytic activity .It provided a practical and environmentally friendly method for the synthesis of 4H-chromene derivatives and had a good potential in industrial application .