CAJ | 학술논문

建立了液相色谱-串联质谱法同时测定带鱼中三甲基锡（TMT）、二苯基锡（DPhT）、二丁基锡（DBT）、三苯基锡（TPhT）和三丁基锡（TBT）分析新方法。采用 ZORBAX Eclipse plus C18色谱柱分离，以甲醇-甲酸/甲酸铵溶液（pH＝2．15）为流动相，在流速0．3 mL·min-1条件下，选择梯度洗脱方式分离目标物。应用液相色谱-串联质谱仪在多重反应监测（MRM）正离子模式下进行检测。有机锡化合物在选定的浓度范围内线性关系良好，相关系数均在0．9943～0．9998之间，三甲基锡、二苯基锡、二丁基锡、三苯基锡和三丁基锡的检测限分别为300、140、140、1和1 ng·mL-1。方法回收率为64．7～96．9％，相对标准偏差为0．7～10．4％。
건립료액상색보-천련질보법동시측정대어중삼갑기석（TMT）、이분기석（DPhT）、이정기석（DBT）、삼분기석（TPhT）화삼정기석（TBT）분석신방법。채용 ZORBAX Eclipse plus C18색보주분리，이갑순-갑산/갑산안용액（pH＝2．15）위류동상，재류속0．3 mL·min-1조건하，선택제도세탈방식분리목표물。응용액상색보-천련질보의재다중반응감측（MRM）정리자모식하진행검측。유궤석화합물재선정적농도범위내선성관계량호，상관계수균재0．9943～0．9998지간，삼갑기석、이분기석、이정기석、삼분기석화삼정기석적검측한분별위300、140、140、1화1 ng·mL-1。방법회수솔위64．7～96．9％，상대표준편차위0．7～10．4％。
A new method was established for the simultaneous determination of trimethyltin (TMT),diphe-nyltin (DPhT),dibutyltin (DBT),triphenyltin (TPhT)and tributyltin (TBT)in hairtail by liquid chroma-tography-tandem mass spectrometry.The separation of five organotin compounds was achieved on ZORB-AX Eclipse plus C18 column with gradient elution using mixture of ammonium formate solution at pH 2.1 (adjusted with formic acid)and methanol.The flow rate was 0.3 mL/min.The detection was operated in the positive ion mode using multiple reaction monitoring.Five organotin compounds all represent good line-arity in the selected concentration range,with correlation coefficients in the range of 0.9943-0.9998.The detection limits of TMT,DPhT,DBT,TPhT and TBT were 300,140,140,1,1 ng·mL-1 ,respectively.Un-der optimized conditions,the average recoveries were ranged from 64.7% to 96.9%,with RSDs from 0.7%to 10.4%,respectively.