CAJ | 학술논문

目的：分析美托洛尔与胺碘酮长期联合应用治疗心房纤颤的临床效果及安全性，为后期临床治疗提供参考。方法选取我院2011年1月~2013年1月我院门诊收入的90例心房纤颤患者作为研究对象，根据治疗方式的不同分为研究组与对照组，每组各45例。对照组患者给予胺碘酮治疗，研究组患者在对照组基础上给予美托洛尔治疗。观察两组患者经治疗后的一般情况。结果两组患者经治疗后的临床总有效率及治疗后的 LVEF、左心房内径比较，差异具有统计学意义（P＜0.05）；两组患者不良反应比较，差异无统计学意义（P＞0.05）。结论美托洛尔联合胺碘酮应用于临床心房颤动治疗，疗效显著，可明显改善患者临床症状，不良反应低，值得临床推广应用。
목적：분석미탁락이여알전동장기연합응용치료심방섬전적림상효과급안전성，위후기림상치료제공삼고。방법선취아원2011년1월~2013년1월아원문진수입적90례심방섬전환자작위연구대상，근거치료방식적불동분위연구조여대조조，매조각45례。대조조환자급여알전동치료，연구조환자재대조조기출상급여미탁락이치료。관찰량조환자경치료후적일반정황。결과량조환자경치료후적림상총유효솔급치료후적 LVEF、좌심방내경비교，차이구유통계학의의（P＜0.05）；량조환자불량반응비교，차이무통계학의의（P＞0.05）。결론미탁락이연합알전동응용우림상심방전동치료，료효현저，가명현개선환자림상증상，불량반응저，치득림상추엄응용。
Objective To analyze the clinical ef ects of metoprolol and amiodarone combination of long-term safety of the treatment of atrial fibril ation and provide reference for late-stage clinical treatment. Methods Hospital during January 2011 January 2013 90 cases of atrial fibril ation patients in our hospital revenue as research subjects, divided according to the dif erent treatment of the study group and the control group , 45 cases in each group . In the control group were treated with amiodarone therapy , the study group were treated with metoprolol treatment in the control group basis. Were observed after treatment in general . Results The clinical groups of patients after treatment of the total ef iciency and after treatment LVEF , left atrial diameter , the dif erence was statistical y significant (P<0.05);two adverse reactions in patients , the dif erence was not statistical y significant (P>0.05 ) . Conclusion Metoprolol and amiodarone used in clinical treatment of atrial fibril ation , a significant ef ect , can significantly improve the clinical symptoms , low adverse reactions , worthy of clinical application.