CAJ | 학술논문

建立了三重串联四级杆液质联用仪法测定塑料杯中双酚A（BPA）迁移量的分析方法。塑料杯经4种模拟液（水、3%乙酸水溶液、10%乙醇溶液和异辛烷）浸泡后，以ZORBAX Eclipce XDB-C18色谱柱分离，进行LC-MS/MS多反应监测模式下定性及定量分析。LC-MS/MS定量限为1.5μg/kg，线性范围为10~500ng/L，相关系数r2=0.9991，平均回收率为78.60%~97.92%，相对标准偏差为2.58％～7.65％（n=6）。
건립료삼중천련사급간액질련용의법측정소료배중쌍분A（BPA）천이량적분석방법。소료배경4충모의액（수、3%을산수용액、10%을순용액화이신완）침포후，이ZORBAX Eclipce XDB-C18색보주분리，진행LC-MS/MS다반응감측모식하정성급정량분석。LC-MS/MS정량한위1.5μg/kg，선성범위위10~500ng/L，상관계수r2=0.9991，평균회수솔위78.60%~97.92%，상대표준편차위2.58％～7.65％（n=6）。
Determination of bisphenol A(BPA)by Triple Quadurupole Liquid Chromatography-Tandem mass Spectrometry (LC-MS/MS)was established. The migration of bisphenol A from plastid cup was soacked by four simulants ,including water,3%(by volume)acetic acid,10%(by volume)ethanol and isooctane using the simulated contact temperature and time. The extract was separated on ZORBAX Eclipce XDB-C18 column.Qualitative and quantitative analyses of bisphenol A was carried out uder MRM mode. The limit of quantitation for bisphenol A migrate from plastic cup was 1.5μg/kg,the mean recoveries from plastic at three spiked levels were 78.60%~97.92%,respectively,with RSD of 2.58%~7.65%.