CAJ | 학술논문

目的：探讨冠心病患者血脂异常及炎症反应与颈动脉斑块形成的关系。方法选择2009-05～2013-04在该院住院治疗的132例冠心病患者，彩超检查颈动脉显示伴有颈动脉斑块形成93例（观察组），不伴有颈动脉斑块39例（对照组）。均常规检测总胆固醇（ TC）、低密度胆固醇（ LDL-C）、甘油三酯（ TG）、高密度胆固醇（ HDL-C）和超敏C反应蛋白（ hs-CRP）。结果观察组血清TC和LDL-C均高于对照组（ P＜0.05或＜0.01），而两组的hs-CRP、TG及HDL-C差异无统计学意义（ P均＞0.05）。结论冠心病患者中高TC和高LDL-C可能与颈动脉斑块形成有关，而hs-CRP与颈动脉斑块形成无明显关联。
목적：탐토관심병환자혈지이상급염증반응여경동맥반괴형성적관계。방법선택2009-05～2013-04재해원주원치료적132례관심병환자，채초검사경동맥현시반유경동맥반괴형성93례（관찰조），불반유경동맥반괴39례（대조조）。균상규검측총담고순（ TC）、저밀도담고순（ LDL-C）、감유삼지（ TG）、고밀도담고순（ HDL-C）화초민C반응단백（ hs-CRP）。결과관찰조혈청TC화LDL-C균고우대조조（ P＜0.05혹＜0.01），이량조적hs-CRP、TG급HDL-C차이무통계학의의（ P균＞0.05）。결론관심병환자중고TC화고LDL-C가능여경동맥반괴형성유관，이hs-CRP여경동맥반괴형성무명현관련。
Objective To investigate whether or not the abnormal blood lipid and inflammatory reaction as-sociated with carotid atherosclerotic plaque formation in patients with coronary heart disease .Methods One hundred and thirty-two coronary heart disease patients with or without carotid atherosclerotic plaque hospitalized in our hospital from May 2009 to April 2013 were enrolled in this study , including 93 patients with carotid atherosclerotic plaque ( ob-servation group ) and 39 patients without carotid atherosclerotic plaque ( control group ) .Total cholesterol ( TC) , low density lipoprotein cholesterol ( LDL-C) , triglyceride ( TG ) , high density lipoprote cholesterol ( HDL-C ) and hyper-sensitive C-reactive protein ( hs-CRP ) in all patients were detected routinely .Results The observation group had higher TC and higher LDL-C than the control group(P<0.05 and P<0.01, respectively).However,TG, HDL-C and hs-CRP between two groups had not statistically significant difference ( P all >0.05 ) .Conclusion In patients with coronary heart disease , higher TC and higher LDL-C may be related with the formation of carotid plaque ,while hs-CRP has not apparently related with the formation of carotid plaque .