CAJ | 학술논문

目的：比较胸部肿瘤调强放射治疗（IMRT）与常规放射治疗（CRT）剂量-体积直方图（DVH）参数及动态心电图（ DCG）的改变情况。方法选择72例胸部肿瘤患者，根据治疗方案分为IMRT组和CRT组，每组36例，分别于治疗前、中、后进行24 h DCG监测，分析两组DVH参数及DCG改变情况。结果 IMRT组心脏V30、V40、V50均明显低于CRT组，差异有统计学意义（ P＜0.01），IMRT组及CRT组治疗前、中、后DCG异常发生率比较，差异有统计学意义（ P＜0.01），治疗中、后IMRT组DCG异常发生率均低于CRT组，差异有统计学意义（P＜0.05）。结论两种治疗方法均可引起DCG改变，但在相同剂量照射时，IMRT组心脏受照体积减少，对DCG影响更小。
목적：비교흉부종류조강방사치료（IMRT）여상규방사치료（CRT）제량-체적직방도（DVH）삼수급동태심전도（ DCG）적개변정황。방법선택72례흉부종류환자，근거치료방안분위IMRT조화CRT조，매조36례，분별우치료전、중、후진행24 h DCG감측，분석량조DVH삼수급DCG개변정황。결과 IMRT조심장V30、V40、V50균명현저우CRT조，차이유통계학의의（ P＜0.01），IMRT조급CRT조치료전、중、후DCG이상발생솔비교，차이유통계학의의（ P＜0.01），치료중、후IMRT조DCG이상발생솔균저우CRT조，차이유통계학의의（P＜0.05）。결론량충치료방법균가인기DCG개변，단재상동제량조사시，IMRT조심장수조체적감소，대DCG영향경소。
Objective To compare the dose volume histogram ( DVH) parameters and dynamic electrocardio-gram( DCG) changes between intensity modulated radiotherapy ( IMRT) and conventional radiotherapy ( CRT) for the thoracic tumor.Methods The patients with thoracic tumors were divided into IMRT group and CRT group ,with 36 cases in every group , two groups were tested with 24-hour DCG before , during and after treatment to compare DVH parameters and DCG changed .Results Heart V30-V50 in IMRT group were significantly lower than that in the CRT group, with statistical significance ( P<0.01 ) , the abnormity incidence rates of DCG was statistically significant be-tween IMRT group and CRT group(before, during and after treatment)(P<0.01), the abnormity incidence rates of DCG were lower in IMRT group than that of CRT group during and after treatment , with statistical significance ( P<0.05 ) .Conclusion Both treatments can cause DCG change , but at the same dose IMRT group has smaller heart ir-radiation volume and lighter change of DCG .