CAJ | 학술논문

目的：观察预防性抗生素应用在重症急性胰腺炎(SAP)治疗中的疗效，改善患者的预后。方法：根据是否预防性使用抗生素将SAP患者分为两组，治疗组35例，对照组27例，观察两组患者的感染发生率、病死率及住院时间之间的差异。结果：治疗组感染发生率和病死率显著低于对照组(P<0.05)，而两组患者之间平均住院时间无明显差异(P>0.05)。结论：预防性抗生素应用对于SAP治疗有一定的临床价值，可降低患者感染发生率及病死率。
목적：관찰예방성항생소응용재중증급성이선염(SAP)치료중적료효，개선환자적예후。방법：근거시부예방성사용항생소장SAP환자분위량조，치료조35례，대조조27례，관찰량조환자적감염발생솔、병사솔급주원시간지간적차이。결과：치료조감염발생솔화병사솔현저저우대조조(P<0.05)，이량조환자지간평균주원시간무명현차이(P>0.05)。결론：예방성항생소응용대우SAP치료유일정적림상개치，가강저환자감염발생솔급병사솔。
Objective:To study the roles of prophylactic antibiotics in the treatment of severe acute pancreatitis(SAP). Methods:Patients with SAP weredivided into two groups depending on whether the preventive use of antibiotics. Then the differences of infection incidence, mortality and hospital stay were observed between the two groups. Results:The infection incidence and mortality in the treatment group were significantly lower than control group, but no significant difference in hospital stay between the two groups. Conclusion:The use of prophylactic antibiotics in SAP has some clinical value.