CAJ | 학술논문

目的：观察复方丹参注射液辅助治疗急性肾盂肾炎(AP)的临床疗效及不良反应。方法：72例AP患者随机分为两组，对照组(n=37例)仅根据药敏结果选择敏感抗生素治疗，观察组(n=35例)在敏感抗生素基础上加用复方丹参注射液治疗，两组疗程均为2周。比较两组治疗总有效率和各临床症状体征消失时间。结果：观察组总有效率(88.6%)明显高于对照组(73.0%)(P<0.05)；观察组腰酸痛、神疲乏力和膀胱刺激征消除时间明显快于对照组(P<0.05)；两组治疗期间均未出现严重不良反应。结论：复方丹参注射液辅助治疗AP疗效显著，可快速改善临床症状和体征。
목적：관찰복방단삼주사액보조치료급성신우신염(AP)적림상료효급불량반응。방법：72례AP환자수궤분위량조，대조조(n=37례)부근거약민결과선택민감항생소치료，관찰조(n=35례)재민감항생소기출상가용복방단삼주사액치료，량조료정균위2주。비교량조치료총유효솔화각림상증상체정소실시간。결과：관찰조총유효솔(88.6%)명현고우대조조(73.0%)(P<0.05)；관찰조요산통、신피핍력화방광자격정소제시간명현쾌우대조조(P<0.05)；량조치료기간균미출현엄중불량반응。결론：복방단삼주사액보조치료AP료효현저，가쾌속개선림상증상화체정。
Objective:To observe the clinical effect and adverse reaction of Compound Danshen injection adjunctive treatment of acute pyelonephritis. Methods:72 patients with acute pyelonephritis were randomly divided into two groups, the control group (n=37 cases) was only treated with sensitive antibiotics based on the results of drug sensitivity, and the observation group (n=35 cases) was treated with Compound Danshen injection base on the sensitive antibiotics, two groups were treated for 2 weeks. The total effective rate and disappear time of clinical symptoms in two groups were compared. Results:The total effective rate of observation group (88.6%) was significantly higher than that of control group (73%)(P<0.05).The disappear time of lumbar pain, lassitude and bladder irritation in observation group was significantly faster than that of control group(P<0.05). There was no serious adverse reaction occurred during the treatment of two groups. Conclusion:The adjunctive treatment of Compound Danshen injection for acute pyelonephritis had a significant curative effect. It could rapidly improve the clinical symptoms and signs. It was worthy of clinical application.