医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2014年
3期
90-91
,共2页
吴陈棠(通讯作者)%叶巍%陈雪云
吳陳棠(通訊作者)%葉巍%陳雪雲
오진당(통신작자)%협외%진설운
参松养心胶囊%窦性心率震荡%室性早搏,特发性
參鬆養心膠囊%竇性心率震盪%室性早搏,特髮性
삼송양심효낭%두성심솔진탕%실성조박,특발성
Shengsongyangxin capsule%Heart rate turbulence(HRT)%Idiopathic premature ventricular contraction (IPVCs)
目的：评价参松养心胶囊对特发性室性早搏（IPVCs）不同早搏负荷患者窦性心率震荡（HRT）的影响。方法：按不同早搏负荷，将94例IPVCs患者分为高负荷组30例、中负荷组36例、低负荷组28例，比较各组参松养心胶囊治疗前后HRT参数震荡初始（TO）和震荡斜率（TS）变化。结果：三组治疗后，低负荷组TO、TS无明显改善（P＞0.05），高、中负荷组TO、TS均有明显改善（P均<0.05），尤以高负荷组改善更显著。结论：参松养心胶囊能改善IPVCs高、中早搏负荷患者的HRT，早搏负荷越重其改善程度越佳；HRT改善程度可作为药物治疗IPVCs的疗效衡量指标。
目的：評價參鬆養心膠囊對特髮性室性早搏（IPVCs）不同早搏負荷患者竇性心率震盪（HRT）的影響。方法：按不同早搏負荷，將94例IPVCs患者分為高負荷組30例、中負荷組36例、低負荷組28例，比較各組參鬆養心膠囊治療前後HRT參數震盪初始（TO）和震盪斜率（TS）變化。結果：三組治療後，低負荷組TO、TS無明顯改善（P＞0.05），高、中負荷組TO、TS均有明顯改善（P均<0.05），尤以高負荷組改善更顯著。結論：參鬆養心膠囊能改善IPVCs高、中早搏負荷患者的HRT，早搏負荷越重其改善程度越佳；HRT改善程度可作為藥物治療IPVCs的療效衡量指標。
목적：평개삼송양심효낭대특발성실성조박（IPVCs）불동조박부하환자두성심솔진탕（HRT）적영향。방법：안불동조박부하，장94례IPVCs환자분위고부하조30례、중부하조36례、저부하조28례，비교각조삼송양심효낭치료전후HRT삼수진탕초시（TO）화진탕사솔（TS）변화。결과：삼조치료후，저부하조TO、TS무명현개선（P＞0.05），고、중부하조TO、TS균유명현개선（P균<0.05），우이고부하조개선경현저。결론：삼송양심효낭능개선IPVCs고、중조박부하환자적HRT，조박부하월중기개선정도월가；HRT개선정도가작위약물치료IPVCs적료효형량지표。
Objective: To explore the effect of heart rate turbulence (HRT) in patients with different degree load of idiopathic premature ventricular contractions (IPVCs) after Shengsongyangxin capsule therapy. Methods: A total of 94 patients with IPVCs was divided into three groups by the load of contractions in different degrees: high-load group(n=30), moderate-load group(n=36)and low-load group(n=28), compared the change in values of turbulence onset (TO) and turbulence slope (TS) of HRT parameters amongst different groups before and after Shengsongyangxin capsule treatment. Results: There were significantly improved of TO and TS of the moderate-load and high-load groups, compared to pre therapy (P<0.05), especial y high-load group; While, there were no significantly improved of TO and TS of the low-load group, compared to pre therapy (P>0.05). Conclusions: Shengsongyangxin capsule therapy could improve the HRT of patients with moderate-load or high-load IPVCs,the larger the load, the more the improvement; The scale of improvement of HRT could be a good maker to assess the effectiveness of drug for the treatment of IPVCs.
