CAJ | 학술논문

目的探讨阿尔茨海默病(AD)患者的脑电图(EEG)和脑血流(CBF)表现,评价其与诊断、预后及治疗的关系.方法对93例经临床确诊的AD患者进行EEG和经颅多普勒超声(TCD)检查,分析EEG异常程度与痴呆严重程度的关系,以及AD患者的脑血流改变.结果93例患者中EEG正常4例,占4.3%;异常89例,占95.7%.患者痴呆程度越重.EEG异常也越明显.AD组MCA及BA的峰值流速(Vp)、平均流速(Vm)较对照组低,而血管搏动指数(PI)则较对照组高,差异有统计学意义(P<0.05和P<0.01).结论EEG、TCD检查对AD的诊断、鉴别诊断、预后判断及指导治疗有实用价值.
목적 탐토아이자해묵병(AD)환자적뇌전도(EEG)화뇌혈류(CBF)표현,평개기여진단、예후급치료적관계.방법대93례경림상학진적AD환자진행EEG화경로다보륵초성(TCD)검사,분석EEG이상정도여치태엄중정도적관계,이급AD환자적뇌혈류개변.결과93례환자중EEG정상4례,점4.3%;이상89례,점95.7%.환자치태정도월중.EEG이상야월명현.AD조MCA급BA적봉치류속(Vp)、평균류속(Vm)교대조조저,이혈관박동지수(PI)칙교대조조고,차이유통계학의의(P<0.05화P<0.01).결론EEG、TCD검사대AD적진단、감별진단、예후판단급지도치료유실용개치.
Objective To investigate the characteristica of eleetroencephalogram(EEG) and cerebral blood flow(CBF) of patients with Alzheimer disease(AD) and evaluate the relationship between EEG abnormalities and patients' prognosis, prognosis as well as CBF and treatment.Methods EEG and transcranial Doppler(TCD) was performed in 93 patients with AD proved by clinic. The relationship be-tween degree of EEG abnormalities and patients' prognosis as well as the change of CBF was analyzed Results Of the EEG of 93 cases involved in the study,4(4.3％) was normal,89(95.7％) had abnormalities The higher degree of EEG abnormality,the severer degree of dementia.Comparisons With control group,the systole peak flow velocity(Vp) and mean flow velocity(Vm) in AD group were dropped,while the pulsating index(PI) enhanced(P<0.05 or P<0.01).Conclusions EEG and TCD is worthy for the diagnosis, differential diagnosis, deciding prognosis and directing treatment of AD.