中国实用医药
中國實用醫藥
중국실용의약
CHINA PRACTICAL MEDICAL
2014年
6期
36-37
,共2页
HBV%MDSCs%流式细胞术
HBV%MDSCs%流式細胞術
HBV%MDSCs%류식세포술
HBV%MDSCs%Flow cytometry
目的：探讨并分析正常人对照组及慢性乙型肝炎患者外周血中MDSCs含量与病毒载体、疾病预后的关系。方法分别用流式细胞仪检测健康人和慢性乙型肝炎患者外周血MDSCs含量，并进行病毒载量和疾病预后资料的相关分析。结果慢性乙型肝炎组的MDSCs百分含量相与正常对照组相比，显著增多(P<0.05)；而且通过病例资料分析发现MDSCs含量不仅随着慢性HBV病重程度逐级升高，而且与慢性乙肝疾病预后HBV-DNA含量密切相关。结论 MDSCs可作为慢性乙型肝炎的一种新型血清标志物，用于患者的诊断和预后指标。
目的：探討併分析正常人對照組及慢性乙型肝炎患者外週血中MDSCs含量與病毒載體、疾病預後的關繫。方法分彆用流式細胞儀檢測健康人和慢性乙型肝炎患者外週血MDSCs含量，併進行病毒載量和疾病預後資料的相關分析。結果慢性乙型肝炎組的MDSCs百分含量相與正常對照組相比，顯著增多(P<0.05)；而且通過病例資料分析髮現MDSCs含量不僅隨著慢性HBV病重程度逐級升高，而且與慢性乙肝疾病預後HBV-DNA含量密切相關。結論 MDSCs可作為慢性乙型肝炎的一種新型血清標誌物，用于患者的診斷和預後指標。
목적：탐토병분석정상인대조조급만성을형간염환자외주혈중MDSCs함량여병독재체、질병예후적관계。방법분별용류식세포의검측건강인화만성을형간염환자외주혈MDSCs함량，병진행병독재량화질병예후자료적상관분석。결과만성을형간염조적MDSCs백분함량상여정상대조조상비，현저증다(P<0.05)；이차통과병례자료분석발현MDSCs함량불부수착만성HBV병중정도축급승고，이차여만성을간질병예후HBV-DNA함량밀절상관。결론 MDSCs가작위만성을형간염적일충신형혈청표지물，용우환자적진단화예후지표。
Objective To investigate the relationship between the analysis and the normal control group and chronic hepatitis B in the peripheral blood of patients with viral vectors, MDSCs content and the prognosis of the disease. Methods Patients with healthy people were detected by flow cytometry and chronic hepatitis B, peripheral blood MDSCs content, correlation analysis and viral load and disease outcome data. Results the percentage of MDSCs phase and the chronic hepatitis B group compared with the normal control group, increased significantly (P<0.05);and through the case analysis found that MDSCs was not only with chronic HBV severity gradually increased, and closely related to chronic hepatitis B disease prognosis HBV-DNA content. Conclusion MDSCs can be used as a new type of chronic hepatitis B serum marker for diagnosis and prognosis, patients.
