CAJ | 학술논문

目的：探讨顺铂和多西紫杉醇联合放疗在治疗食管癌中的应用价值。方法将2011年3月-2013年3月湖南省新晃县人民医院收治的92例食管癌患者按不同治疗方法均分为对照组（单纯放疗）和实验组（同步放化疗），对两组的疗效、生存率、毒副作用进行综合比较。结果实验组患者治疗有效率（89.13%）明显就高于对照组患者（63.04%），差异有统计学意义（P＜0.05）；实验组患者2年生存率、3生存率、中位生存时间均高于对照组患者，差异有统计学意义（P＜0.05）；两组患者毒副作用发生率比较，差异无统计学意义。结论顺铂和多西紫杉醇联合放疗用于治疗食管癌效果显著，能提高患者生存率和中位生存时间。
목적：탐토순박화다서자삼순연합방료재치료식관암중적응용개치。방법장2011년3월-2013년3월호남성신황현인민의원수치적92례식관암환자안불동치료방법균분위대조조（단순방료）화실험조（동보방화료），대량조적료효、생존솔、독부작용진행종합비교。결과실험조환자치료유효솔（89.13%）명현취고우대조조환자（63.04%），차이유통계학의의（P＜0.05）；실험조환자2년생존솔、3생존솔、중위생존시간균고우대조조환자，차이유통계학의의（P＜0.05）；량조환자독부작용발생솔비교，차이무통계학의의。결론순박화다서자삼순연합방료용우치료식관암효과현저，능제고환자생존솔화중위생존시간。
Objective To investigate the application of docetaxel and cisplatin combined with radiotherapy in treating esophageal cancer. Methods 92 cases patients with esophageal cancer in our hospital from March 2011 to March 2013 were divided into control group(radiotherapy) and experimental group(chemotherapy+radiotherapy),the efficacy,survive-rate,side-reaction rate of two groups were compared.Results The total effective-rate of experimental group(89.13%) was higher than that of control group(63.04%)(P<0.05);the survive-rate of 2,3 years and median survival in experimental group were higher than that in control group(P<0.05);no significant difference was observed in side-reaction rate between two groups. Conclusion Docetaxel and cisplatin combined with radiotherapy has a significant effects on treating esophageal cancer,it can improve the survive-rate and median survival.