CAJ | 학술논문

目的：探讨Ⅰ期切除吻合术在大肠癌合并肠梗阻患者中的应用效果。方法将山东大学齐鲁医院青岛院区收治的64例大肠癌合并肠梗阻患者随机分为观察组和对照组，每组32例。观察组患者采取Ⅰ期切除吻合术治疗，对照组患者采取姑息性手术治疗，观察两组患者的临床疗效、术后并发症及3年生存率情况。结果两组患者治疗后梗阻症状均得到了显著改善，观察组患者术后并发症发生率为3.1%，明显低于对照组患者的21.9%，组间差异有统计学意义（P＜0.05）；观察组患者的3年生存率为96.9%，明显高于对照组患者的84.4%，组间差异有统计学意义（P＜0.05）。结论 I期切除吻合术治疗大肠癌合并肠梗阻患者临床疗效好，安全性高，是一种理想的治疗术式。
목적：탐토Ⅰ기절제문합술재대장암합병장경조환자중적응용효과。방법장산동대학제로의원청도원구수치적64례대장암합병장경조환자수궤분위관찰조화대조조，매조32례。관찰조환자채취Ⅰ기절제문합술치료，대조조환자채취고식성수술치료，관찰량조환자적림상료효、술후병발증급3년생존솔정황。결과량조환자치료후경조증상균득도료현저개선，관찰조환자술후병발증발생솔위3.1%，명현저우대조조환자적21.9%，조간차이유통계학의의（P＜0.05）；관찰조환자적3년생존솔위96.9%，명현고우대조조환자적84.4%，조간차이유통계학의의（P＜0.05）。결론 I기절제문합술치료대장암합병장경조환자림상료효호，안전성고，시일충이상적치료술식。
Objective To explore the effect of one-stage resection-anastomosis in patients of colorectal cancer with intestinal obstruction. Methods 64 cases of colorectal cancer with intestinal obstruction in the hospital were randomly divided into observation group and control group, 32 cases in each group.Patients in observation group were taken one-stage resection-anastomosis operation, cases in control group were taken palliative operation, observed the clinical effect, postoperative complications and 3 year survival rate. Results After treatment the obstructive symptoms of all patients were improved signiifcantly, the rate of complication was 3.1%in observation group, signiifcantly lower than that in control group (21.9%), there was signiifcant difference between two groups (P<0.05), the 3 year survival rate of patients in observation group was 96.9%, signiifcantly higher than that in control group (84.4%), there was signiifcant difference between two groups (P<0.05). Conclusion Taking one-stage resection-anastomosis operation in patients with colorectal cancer has good clinical effect and high safety, it is an ideal surgical treatment.