CAJ | 학술논문

目的探讨屎肠球菌的分布及耐药性,为临床合理使用抗菌药物提供依据.方法回顾性分析屎肠球菌的耐药性,总结标本类型、科室分布等情况,探讨耐药性的变化趋势.结果 2010年1月至2013年12月每年屎肠球菌分离率呈递增趋势,且耐万古霉素屎肠球菌分离率也逐年增加.屎肠球菌万古霉素耐药率由2010年的3.54％(4/113),上升到2013年的8.45％(18/213).717株中发现1株利奈唑胺耐药屎肠球菌,其最低抑菌浓度为7.9 mg/L,未发现替加环素耐药的屎肠球菌.结论耐万古霉素屎肠球菌对于利奈唑胺和替加环素的敏感性仍很高,这两种抗菌药物可用于耐万古霉素屎肠球菌的治疗.
목적 탐토시장구균적분포급내약성,위림상합리사용항균약물제공의거.방법 회고성분석시장구균적내약성,총결표본류형、과실분포등정황,탐토내약성적변화추세.결과 2010년1월지2013년12월매년시장구균분리솔정체증추세,차내만고매소시장구균분리솔야축년증가.시장구균만고매소내약솔유2010년적3.54％(4/113),상승도2013년적8.45％(18/213).717주중발현1주리내서알내약시장구균,기최저억균농도위7.9 mg/L,미발현체가배소내약적시장구균.결론 내만고매소시장구균대우리내서알화체가배소적민감성잉흔고,저량충항균약물가용우내만고매소시장구균적치료.
Objective To investigate the distribution and drug resistance ofEnterococcus faecium,provide evidence for clinical rational use of antimicrobial agents.Methods Retrospective analysis of drug resistance of Enterococcus faecium,summarize the specimen type,distribution of departments and so on,to explore the trend of drug resistance.Results Enterococcus faecium to vancomycin resistance rate from 3.54％ (4/113) in 2010,rose to 8.45％ (18/213) in 2013.One strains of hnezolid resistant Enterococcus faecium 717 was found,the minimum inhibitory concentration of 7.9 mg/L,not tigecycline resistance in Enterococcus faecium found.Conclusion Vancomycin resistant Enterococcus faecium for linezolid and tigecycline susceptibility is still high,the two kinds of antimicrobial agents can be used for the treatment of vancomycin resistant Enterococcus faecium.