中国骨科临床与基础研究杂志
中國骨科臨床與基礎研究雜誌
중국골과림상여기출연구잡지
CHINESE JOURNAL OF CLINICAL AND BASIC ORTHO[AEDIC RESEARCH
2014年
2期
118-122
,共5页
陈加荣%张余%黄华扬%夏虹%尹庆水
陳加榮%張餘%黃華颺%夏虹%尹慶水
진가영%장여%황화양%하홍%윤경수
骨髓间充质干细胞%软骨缺损%磁力%靶向传递
骨髓間充質榦細胞%軟骨缺損%磁力%靶嚮傳遞
골수간충질간세포%연골결손%자력%파향전체
Bone marrow mesenchymal stem cells%Cartilage defect%Magnetic force%Targeted delivering
关节软骨缺损修复一直是国内外研究的热点与难点。骨髓间充质干细胞移植技术具有良好的应用前景,但干细胞靶向问题亟待解决。该文阐述干细胞靶向传递的新策略--磁力靶向传递技术,重点介绍该技术应用于修复关节软骨缺损的背景、优势及存在的技术难点,并对该技术的应用前景进行展望。
關節軟骨缺損脩複一直是國內外研究的熱點與難點。骨髓間充質榦細胞移植技術具有良好的應用前景,但榦細胞靶嚮問題亟待解決。該文闡述榦細胞靶嚮傳遞的新策略--磁力靶嚮傳遞技術,重點介紹該技術應用于脩複關節軟骨缺損的揹景、優勢及存在的技術難點,併對該技術的應用前景進行展望。
관절연골결손수복일직시국내외연구적열점여난점。골수간충질간세포이식기술구유량호적응용전경,단간세포파향문제극대해결。해문천술간세포파향전체적신책략--자력파향전체기술,중점개소해기술응용우수복관절연골결손적배경、우세급존재적기술난점,병대해기술적응용전경진행전망。
As a reseach focus all over the world, articular cartilage defect repair with bone marrow derived mesenchymal stem cells (BMSCs) has a big dilemma need to be solved firstly. That is how to target the stem cells into progenitor cells. Technical breakthrough of targeted delivering methods will be helpful for cell therapy, and provide a new approach for cartilage tissue engineering. In this paper, a new method of BMSCs delivering by magnetic force was discussed. The origin, advantages and difficulties of this technique were mainly introduced and the prospects were outlined at the same time.