CAJ | 학술논문

目的探讨辅助生殖技术( Assisted Reproductive Technology, ART)婴幼儿的体格发育情况,评价ART的安全性。方法计算机检索中国学术期刊网络出版总库,维普中文科技期刊全文数据库,中国博士学位论文全文数据库, PubMed, EBSCO 全文数据库,德国 SPRINGER 公司期刊数据库,和 Cochrane Library 等,并辅助其他检索方式,纳入 ART术后妊娠和自然妊娠( Nature conceived, NC)出生的0~3岁婴幼儿体格发育状况比较的队列研究,并使用 RevMan 5.0进行 Meta分析。结果 meta分析结果显示辅助生殖技术子代体格发育与自然妊娠儿相比,差异无统计学意义( P=0.14)。其 OR (95%CI)为OR=1.80,95%CI (0.83,3.92)。结论辅助生殖技术婴幼儿生长发育与自然妊娠儿无差异,提示ART不影响婴幼儿体格发育。
목적탐토보조생식기술( Assisted Reproductive Technology, ART)영유인적체격발육정황,평개ART적안전성。방법계산궤검색중국학술기간망락출판총고,유보중문과기기간전문수거고,중국박사학위논문전문수거고, PubMed, EBSCO 전문수거고,덕국 SPRINGER 공사기간수거고,화 Cochrane Library 등,병보조기타검색방식,납입 ART술후임신화자연임신( Nature conceived, NC)출생적0~3세영유인체격발육상황비교적대렬연구,병사용 RevMan 5.0진행 Meta분석。결과 meta분석결과현시보조생식기술자대체격발육여자연임신인상비,차이무통계학의의( P=0.14)。기 OR (95%CI)위OR=1.80,95%CI (0.83,3.92)。결론보조생식기술영유인생장발육여자연임신인무차이,제시ART불영향영유인체격발육。
Objective To evaluate the safety of ART by assessing physical development of children born with assisted reproduc-tive technology ( ART) . Methods Cohort study of the comparison between physical development of 0~ 3-year-old children con-ceived by assisted reproductive technology and by nature conceived ( NC) was conducted in China Academic Journal Network Publish-ing Database, VIP Database for Chinese Technical Periodicals, China Doctoral Dissertations Full-text Database, PubMed, EBSCO, Springer-Link, Cochrane Library and other relevant resource websites. Assisted by RevMan 5.0, the result was processed by meta a-nalysis. Results Results of meta analysis showed that in terms of physical growth of children, there was no statistically significant difference between the assisted reproductive technology and natural pregnancy . (P=0.14) OR ( 95%CI) =1.80, 95%CI (0.83, 3.92). Conclusion Assisted reproductive technology does not affect the physical development of infants.