CAJ | 학술논문

目的：探讨医院人群血清乙型肝炎病毒（HBV ）血清学标志物的分布特征，为乙型肝炎预防与控制提供依据。方法收集接受HBV血清学检测的医院人员11210例，将其按年龄分为：＞0～25岁组（n＝3553）、＞25～50岁组（n＝7651）。采用酶联免疫吸附测定（ELISA ）及Roche Cobas E601型全自动电化学发光免疫分析仪检测血清 HBV表面抗原（HBsAg ）、抗HBV表面抗体（HBsAb）、HBV e抗原（HBeAg）、抗 HBV e抗体（HBeAb）及抗 HBV核心抗体（HBcAb）。结果＞0～25岁组、＞25～50岁组受检者 HBsAg 阳性率分别为16．16％、21．19％。总体 HBsAg、HBsAb阳性率及全阴性率为19．59％（2195/11204）、37．02％（4148/11204）及11．84％（1327/11204）。结论医院人群血清 HBV标志物分布特征可为采取有效的乙型肝炎防控措施提供了可靠依据。
목적：탐토의원인군혈청을형간염병독（HBV ）혈청학표지물적분포특정，위을형간염예방여공제제공의거。방법수집접수HBV혈청학검측적의원인원11210례，장기안년령분위：＞0～25세조（n＝3553）、＞25～50세조（n＝7651）。채용매련면역흡부측정（ELISA ）급Roche Cobas E601형전자동전화학발광면역분석의검측혈청 HBV표면항원（HBsAg ）、항HBV표면항체（HBsAb）、HBV e항원（HBeAg）、항 HBV e항체（HBeAb）급항 HBV핵심항체（HBcAb）。결과＞0～25세조、＞25～50세조수검자 HBsAg 양성솔분별위16．16％、21．19％。총체 HBsAg、HBsAb양성솔급전음성솔위19．59％（2195/11204）、37．02％（4148/11204）급11．84％（1327/11204）。결론의원인군혈청 HBV표지물분포특정가위채취유효적을형간염방공조시제공료가고의거。
Objective To investigate the distribution characteristics of serum hepatitis B virus (HBV) markers of population in hospital and to provide the basis for prevention and control of virus B hepatitis .Methods 11 210 people in hospital who had accepted HBV serological testing were enrolled ,and were divided into >0 -25-year old group(n=3 553) and >25 -50-year old group(n=7 651) according to their ages .Enzyme-linked Immunosorbent Assay(ELISA) and Roche Cobas E601 Automatic Electro-chemiluminescence immunoassay analyzer were employed to detect serum HBV surface antigen (HBsAg ) ,anti-HBV surface anti-body(HBsAb) ,HBV e antigen(HBeAg) ,anti-HBV e antibody(HBeAb) and anti-HBV core antibody(HBcAb) .Results HBsAg positive rates of subjects in > 0 -25-year old group and > 25 -50-year old group were 16 .16% and 21 .19% ,respectively .The overall positive rates of HBsAg and HBsAb and full-negative rate were 19 .59% (2 195/11 204) ,37 .02% (4 148/11 204) and 11 .84% (1 327/11 204) ,respectively .Conclusion Distribution characteristics of HBV markers of population in hospital may pro-vide a reliable basis for taking effective protective and control measures against virus B hepatitis .