中国全科医学
中國全科醫學
중국전과의학
CHINESE GENERAL PRACTICE
2014年
15期
1707-1709,1722
,共4页
脑梗死%出血转化%危险因素
腦梗死%齣血轉化%危險因素
뇌경사%출혈전화%위험인소
Brain infarction%Hemorrhagic transformation%Risk factor
目的：探讨急性脑梗死出血转化（HT）的相关危险因素。方法选取2011年6月-2013年6月在本院治疗的急性脑梗死患者818例，其中 HT 135例（16.5%）（观察组），无 HT 683例（83.5%）（对照组）。回顾性分析并比较两组患者的临床指标，经单因素 t 检验、χ2检验及非条件多因素 Logistic 回归分析，筛选急性脑梗死 HT 的相关危险因素。结果观察组患者糖尿病、冠心病、心房纤颤、空腹高血糖、蛋白尿、大面积脑梗死的发生率及空腹血糖水平均高于对照组（P <0.05），饮酒率低于对照组（P <0.05）。Logistic 回归分析显示，糖尿病、心房纤颤、大面积脑梗死是急性脑梗死 HT 的独立危险因素（OR 值分别为1.787、1.802和6.477，均 P <0.05）。结论糖尿病、心房纤颤、大面积脑梗死是急性脑梗死 HT 的独立危险因素。
目的：探討急性腦梗死齣血轉化（HT）的相關危險因素。方法選取2011年6月-2013年6月在本院治療的急性腦梗死患者818例，其中 HT 135例（16.5%）（觀察組），無 HT 683例（83.5%）（對照組）。迴顧性分析併比較兩組患者的臨床指標，經單因素 t 檢驗、χ2檢驗及非條件多因素 Logistic 迴歸分析，篩選急性腦梗死 HT 的相關危險因素。結果觀察組患者糖尿病、冠心病、心房纖顫、空腹高血糖、蛋白尿、大麵積腦梗死的髮生率及空腹血糖水平均高于對照組（P <0.05），飲酒率低于對照組（P <0.05）。Logistic 迴歸分析顯示，糖尿病、心房纖顫、大麵積腦梗死是急性腦梗死 HT 的獨立危險因素（OR 值分彆為1.787、1.802和6.477，均 P <0.05）。結論糖尿病、心房纖顫、大麵積腦梗死是急性腦梗死 HT 的獨立危險因素。
목적：탐토급성뇌경사출혈전화（HT）적상관위험인소。방법선취2011년6월-2013년6월재본원치료적급성뇌경사환자818례，기중 HT 135례（16.5%）（관찰조），무 HT 683례（83.5%）（대조조）。회고성분석병비교량조환자적림상지표，경단인소 t 검험、χ2검험급비조건다인소 Logistic 회귀분석，사선급성뇌경사 HT 적상관위험인소。결과관찰조환자당뇨병、관심병、심방섬전、공복고혈당、단백뇨、대면적뇌경사적발생솔급공복혈당수평균고우대조조（P <0.05），음주솔저우대조조（P <0.05）。Logistic 회귀분석현시，당뇨병、심방섬전、대면적뇌경사시급성뇌경사 HT 적독립위험인소（OR 치분별위1.787、1.802화6.477，균 P <0.05）。결론당뇨병、심방섬전、대면적뇌경사시급성뇌경사 HT 적독립위험인소。
Objective To explore the relevant risk factors for hemorrhagic transformation(HT)after acute cerebral infarction. Methods A total of 818 patients with acute cerebral infarction who were treated in our hospital from June 2011 to June 2013,were selected as study subjects,observation group included 135( 16. 5% ) HT cases,control group included 683 (83. 5% )non - HT cases. Clinical indicators were analyzed retrospectively,and were compared between two groups. Univariate t - test,chi - square test and non - conditional Logistic regression analysis were performed to detect the relevant risk factors for HT after acute cerebral infarction. Results Prevalence of diabetes mellitus,coronary heart disease,atrial fibrillation,hypergly-cemia,proteinuria,massive cerebral infarction and fasting glucose level in observation group were significantly higher than those in control group(P < 0. 05),but prevalence of drinking in observation group was significantly lower than that in control group (P < 0. 05). The results of multivariate Logistic regression analysis revealed that diabetes mellitus〔 OR = 1. 787,95% CI (1. 186,2. 691),P = 0. 005〕,atrial fibrillation〔OR = 1. 802,95% CI(1. 112,9. 919),P = 0. 017〕,and massive cere-bral infarction〔OR = 6. 477,95% CI(4. 198,9. 991),P = 0. 000〕were independent risk factors for HT after acute cerebral infarction. Conclusion Diabetes mellitus,atrial fibrillation and massive cerebral infarction are the independent risk factors for HT after acute cerebral infarction.
