CAJ | 학술논문

背景：牙槽骨牵张成骨是解决严重牙槽骨萎缩的重要方法，其成骨过程和生物力学对于以后的种植和修复极为重要，目前一直缺少相关的实验研究。 　　目的：分析犬牙槽骨牵张成骨的生物力学和组织学特点。 　　方法：先拔除12只杂种犬双侧下颌前磨牙，牙槽骨修整后，制作萎缩牙槽骨模型。3个月后，植入骨内型牙槽骨牵张器。经过7 d的间歇期，以1 mm/d，1次/d的频率进行牙槽骨垂直向增高。在固定期的1，2和3个月，对牵张后的牙槽骨进行临床、生物力学、放射学和组织学检测。 　　结果与结论：所有牵张器与周围组织愈合良好。牵张结束时，临床和放射学检查显示：萎缩牙槽骨分别增高(4.80±0.50) mm和(5.12±0.67) mm。组织学检测发现牵张区骨小梁在固定期的1-3个月成熟，其剪切力逐步提高，固定期3个月时和自体骨的剪切力相当。结果显示牙槽骨牵张成骨的组织学和生物力学性能在固定期3个月时与自体骨相当。
배경：아조골견장성골시해결엄중아조골위축적중요방법，기성골과정화생물역학대우이후적충식화수복겁위중요，목전일직결소상관적실험연구。 　　목적：분석견아조골견장성골적생물역학화조직학특점。 　　방법：선발제12지잡충견쌍측하합전마아，아조골수정후，제작위축아조골모형。3개월후，식입골내형아조골견장기。경과7 d적간헐기，이1 mm/d，1차/d적빈솔진행아조골수직향증고。재고정기적1，2화3개월，대견장후적아조골진행림상、생물역학、방사학화조직학검측。 　　결과여결론：소유견장기여주위조직유합량호。견장결속시，림상화방사학검사현시：위축아조골분별증고(4.80±0.50) mm화(5.12±0.67) mm。조직학검측발현견장구골소량재고정기적1-3개월성숙，기전절력축보제고，고정기3개월시화자체골적전절력상당。결과현시아조골견장성골적조직학화생물역학성능재고정기3개월시여자체골상당。
BACKGROUND:Alveolar distraction osteogenesis is an important method for treating alveolar bone atrophy, the osteogenesis process and biomechanics play a crucial role in the fol owing implantation and repair. At present, no related experimental studies are found. OBJECTIVE:To analyze the biomechanical and histological characteristics of alveolar distraction osteogenesis in a canine model. METHODS:Twelve adult mongrel canines received premolars extraction and alveoloplasty in mandible to establish an atrophy alveolar model. After 3 months, a segmental alveolar osteotomy was performed in the randomly selected unilateral atrophy alveolar and two intra-osseous distractors were placed. After a 7-days latency period, the alveolar ridge was augmented at a rate of 1.0 mm/d for 5 days. After a consolidation of 1, 2, and 3 months, the canines were sacrificed and the specimens of the distracted alveolar bone were harvested for clinical, radiographic, histological and biomechanical analysis. RESULTS AND CONCLUSION:The alveolar distractors obtained good healing with surrounding tissue. The atrophy alveolar bones were augmented for (4.80±0.50) mm and (5.12±0.47) mm by clinical and radiographic findings immediately after distraction, respectively. The bone trabeculae in the distracted chamber matured from 1 to 3 months of consolidation by histological analysis. The shearing force of alveolar distraction chamber increased from 1 to 3 months. After 3 months’ consolidation, the shearing force of distracted chamber was comparable to host bone. The histological and biomechanical property of distracted alveolar chamber is comparable to host bone after 3 months’ consolidation.