CAJ | 학술논문

目的：探讨腹腔镜辅助远端胃癌根治术与开腹根治术的临床疗效和安全性。方法将90例远端胃癌患者随机分为给予腹腔镜手术的观察组和开腹手术的对照组，观察术中相关指标、血清C反应蛋白（ CRP ）、癌胚抗原（CEA）、糖类抗原72-4（CA72-4）、术后恢复指标。结果2组患者在手术时间、切缘与病灶的距离方面的差异无统计学意义；观察组术中出血量（101．6±13．9）ml、CRP（15．7±6．3）mg/L、CEA（6．2±1．4）ng/ml、CE72-4（9．5±3．2）U/ml、术后肛门首次排气时间（3．3±0．6）d、术后进食时间（3．8±1．1）d、镇痛药使用次数（4．2±0．7）、总住院时间（10．6±2．4）d明显低于对照组；淋巴结清扫数目（18．4±3．2）明显多于对照组（P＜0．05）。结论腹腔镜手术能有效进行淋巴结清扫、减小手术创伤、促进术后胃肠功能恢复、改善患者预后，是治疗胃癌有效、安全的方式。
목적：탐토복강경보조원단위암근치술여개복근치술적림상료효화안전성。방법장90례원단위암환자수궤분위급여복강경수술적관찰조화개복수술적대조조，관찰술중상관지표、혈청C반응단백（ CRP ）、암배항원（CEA）、당류항원72-4（CA72-4）、술후회복지표。결과2조환자재수술시간、절연여병조적거리방면적차이무통계학의의；관찰조술중출혈량（101．6±13．9）ml、CRP（15．7±6．3）mg/L、CEA（6．2±1．4）ng/ml、CE72-4（9．5±3．2）U/ml、술후항문수차배기시간（3．3±0．6）d、술후진식시간（3．8±1．1）d、진통약사용차수（4．2±0．7）、총주원시간（10．6±2．4）d명현저우대조조；림파결청소수목（18．4±3．2）명현다우대조조（P＜0．05）。결론복강경수술능유효진행림파결청소、감소수술창상、촉진술후위장공능회복、개선환자예후，시치료위암유효、안전적방식。
Objective To study the efficacy and safety of laparoscopy assisted distal radical gastrectomy and open radi -cal operation for gastric cancer .Methods 90gastric cancer patients were divided into the observation group treated with laparos-copy assisted operation and the control group treated with open operation .The operation related index , serum c-reactive protein (CRP),carcinoembryonic antigen (CEA),carbohydrate antigen 72-4 (CA72-4),and postoperative index were observed .Results There had no statistical difference between the 2 groups in operation time and margin-focal distance;bleeding amount (101.6 ± 13.9)ml,CRP (15.7 ±6.3)mg/L,CEA (6.2 ±1.4)ng/ml,CE72-4 (9.5 ±3.2)U/ml,exhaust time (3.3 ±0.6)d,postopera-tive eating time (3.8 ±1.1)d,analgesic usage (4.2 ±0.7),hospitalization time (10.6 ±2.4)d of the observation group were significantly less than those of the control group;while number of lymph node dissection (18.4 ±3.2) of the observation group was significantly more than that of thecontrol group .Conclusion Laparoscopic surgery can effectively clean lymphocyte ,reduce surgi-cal trauma ,improve gastrointestinal function ,promote prognosis ,it is an effective and safe treatment for gastric cancer .