CAJ | 학술논문

目的：分析近年来泌尿系统感染患者的病原菌分布及耐药性变化，为临床合理用药提供依据。方法收集2012~2013年泌尿系统感染患者尿液标本的细菌培养和药敏检测结果，用SPASS10.0软件进行统计分析研究。结果共分离菌株1133株，其中革兰阴性杆菌632株，占总菌株数的55.8%；其中大肠埃希菌398株，占总菌株数的35.1%，革兰阳性球菌301株占总菌株数的26.6%，真菌200株占总菌株数的17.6%。大肠埃希菌对亚胺培南等碳青霉烯类抗生素均敏感，肠球菌属细菌除铅黄肠球菌外对万古霉素均敏感。结论泌尿系感染病原菌仍以大肠埃希菌为主，真菌感染没有升高的趋势，抗菌药物仍以亚胺培南和万古霉素为首选。
목적：분석근년래비뇨계통감염환자적병원균분포급내약성변화，위림상합리용약제공의거。방법수집2012~2013년비뇨계통감염환자뇨액표본적세균배양화약민검측결과，용SPASS10.0연건진행통계분석연구。결과공분리균주1133주，기중혁란음성간균632주，점총균주수적55.8%；기중대장애희균398주，점총균주수적35.1%，혁란양성구균301주점총균주수적26.6%，진균200주점총균주수적17.6%。대장애희균대아알배남등탄청매희류항생소균민감，장구균속세균제연황장구균외대만고매소균민감。결론비뇨계감염병원균잉이대장애희균위주，진균감염몰유승고적추세，항균약물잉이아알배남화만고매소위수선。
Objective To analysis the current status of the drug-resistance and constitutes of pathogens in patients with urinary tract infections, providing basis for clinical rational drug use. Methods The data of bacteria cultivation and drug susceptibility testing results of Urine specimens from the patients with urinary tract infections during 2012 to 2013 were col ected and analyzed by SPASS10.0 statistical analysis software. Results 1133 pathogenic strains were separated, among them, the strains of Gram-negative bacteria, Gram-positive bacteria and fungus accounting for 632 (55.8%), 301 (26.6%) and 200 (17.6%), respectively. There were 398 strains of E-coli were separated and accounting for 35.1% of the total separated strains. The strains of E-coli were al sensitive to antibiotics of Carbapenems, Enterococcus bacteria strains, except for Enterococcus casseliflavus were al sensitive to Ancomycin. Conclusion E-coli were the main pathogens of Urinary tract infection and Fungal infections had not ascending trend comparing to the previous reports. Imipenem and Ancomycin were the first choice to cure the Urinary tract infection.