CAJ | 학술논문

目的：探讨散结镇痛胶囊联合曼月乐治疗子宫腺肌病的临床效果。方法收集医院收治的子宫腺肌病患者为研究对象，根据入院时间随机分为米非司酮组、曼月乐组、曼月乐联合散结镇痛胶囊组。观察3组患者治疗前和治疗后3个月患者痛经程度、子宫体积、血红蛋白、血清CA125水平，并观察不良反应发生情况。结果治疗后3组患者各项症状均有改善。其中所有患者治疗后均闭经；曼月乐组和曼月乐联合散结镇痛胶囊组痛经评分、子宫体积、CA125下降程度均低于米非司酮组，血红蛋白升高程度高于米非司酮组，差别有统计学意义（P<0.05）；曼月乐联合散结镇痛胶囊组痛经评分、子宫体积、CA125下降程度均低于曼月乐组，差异有统计学意义（P<0.05）。结论散结镇痛胶囊联合曼月乐治疗子宫腺肌病能提高疗效，降低不良反应，具有较好的协同作用，值得临床推广应用。
목적：탐토산결진통효낭연합만월악치료자궁선기병적림상효과。방법수집의원수치적자궁선기병환자위연구대상，근거입원시간수궤분위미비사동조、만월악조、만월악연합산결진통효낭조。관찰3조환자치료전화치료후3개월환자통경정도、자궁체적、혈홍단백、혈청CA125수평，병관찰불량반응발생정황。결과치료후3조환자각항증상균유개선。기중소유환자치료후균폐경；만월악조화만월악연합산결진통효낭조통경평분、자궁체적、CA125하강정도균저우미비사동조，혈홍단백승고정도고우미비사동조，차별유통계학의의（P<0.05）；만월악연합산결진통효낭조통경평분、자궁체적、CA125하강정도균저우만월악조，차이유통계학의의（P<0.05）。결론산결진통효낭연합만월악치료자궁선기병능제고료효，강저불량반응，구유교호적협동작용，치득림상추엄응용。
Objective To explore the clinical effects of Sanjie Snalgesic capsule and mirena in the treatment of uterine adenomyosis. Methods The patients with uterine adenomyosis in our hospital were collected at random,and they were treated with mifepristone, mirena, Sanjie Snalgesic capsule and mirena. The degree of dysmenorrheal, uterine volume, HGB, serum CA125 level of the three groups before and after 3 months treatment were observed. Results After 3 months treatment, the symptoms of three groups were improved effectively. All patients were amenorrhea.The degree of dysmenorrheal, uterine volume, serum CA125 level of the mirena, Sanjie Snalgesic capsule and mirena groups were signiifcantly lower than those in the mifepristone group, otherwise the level of HGB was significantly higher. The degree of dysmenorrheal, uterine volume, serum CA125 level of the Sanjie Snalgesic capsule and mirena group was signiifcantly lower than those in the mirena group. Conclusion The Sanjie Snalgesic capsule and mirena has a good synergy effect in treating uterine adenomyosis, it can improve the clinical effects, reduce the adverse reaction of using myopathy, it is worthy of clinical popularization.