CAJ | 학술논문

[目的]拟探讨新型蒙脱石防治仔猪腹泻的作用机理。[方法]选取30头健康“杜×大×长”三元杂交断奶仔猪，随机分为5组。分别饲喂基础日粮、基础日粮+1 g/kg新型蒙脱石、基础日粮+3 g/kg新型蒙脱石、基础日粮+5 g/kg新型蒙脱石和基础日粮+3 g/kg微生态制剂。4周后动物前腔静脉采血，检测血清中TFF3、NO和 SOD的含量。[结果]与空白对照组相比，新型蒙脱石高剂量组动物血清中TFF3水平极显著升高，NO水平极显著降低， SOD水平显著升高；新型蒙脱石中剂量组动物血清中 TFF3水平显著升高， NO水平显著降低。[结论]新型蒙脱石抗断奶仔猪腹泻的作用机理可能与上调机体 TFF3和 SOD水平，下调NO含量有关。
[목적]의탐토신형몽탈석방치자저복사적작용궤리。[방법]선취30두건강“두×대×장”삼원잡교단내자저，수궤분위5조。분별사위기출일량、기출일량+1 g/kg신형몽탈석、기출일량+3 g/kg신형몽탈석、기출일량+5 g/kg신형몽탈석화기출일량+3 g/kg미생태제제。4주후동물전강정맥채혈，검측혈청중TFF3、NO화 SOD적함량。[결과]여공백대조조상비，신형몽탈석고제량조동물혈청중TFF3수평겁현저승고，NO수평겁현저강저， SOD수평현저승고；신형몽탈석중제량조동물혈청중 TFF3수평현저승고， NO수평현저강저。[결론]신형몽탈석항단내자저복사적작용궤리가능여상조궤체 TFF3화 SOD수평，하조NO함량유관。
[Objective] This study aimed to investigate the mechanism of innovative montmoril onite for diarrhea treatment. [Method] Thirty healthy weanling piglets (Duroc × Landrace × Yorkshire) were randomly divided into five groups and fed with basal diet, basal diet + 1 g/kg innovative montmoril onite, basal diet + 3 g/kg innovative montmoril onite, basal diet + 5 g/kg innovative montmoril onite and basal diet + 3 g/kg Bacil us subtilis microecologic agent, respectively. After four weeks, blood samples were col ected via precaval vein, to detect the content of TFF3, NO and SOD in serum by ELISA kits. [Result] Compared with blank control group, the content of TFF3, NO and SOD in high-dose innovative montmoril onite group was extremely significantly increased, extremely significantly reduced and significantly in-creased, respectively; the content of TFF3 and NO in middle-dose innovative mont-moril onite group was significantly increased and significantly reduced, respectively. [Conclusion] Innovative montmoril onite may exert beneficial therapeutic actions on diarrhea by increasing TFF3 and SOD levels and decreasing NO level.