CAJ | 학술논문

目的：为了更好的观察重症肺炎患者病情变化情况，分析和研究血清降钙素原和C反应蛋白在治疗过程中的变化情况。方法将2010年5月～2013年5月间来河源市源城区人民医院就诊的86例肺炎患者根据病情的严重程度分为观察组和对照组，其中观察组患者43例，均为病情进展期重症肺炎患者，对照组患者43例为轻度肺炎患者，对比和分析2组患者治疗前后血清降钙素原和C-反应蛋白水平的改变情况及与预后的关系。结果重症肺炎组患者的血清降钙素原和C-反应蛋白水平显著高于轻度肺炎组患者，且比较差异具有统计学意义（P<0.05）。结论对于重症肺炎患者其病情变化可将血清降钙素原和 C-反应蛋白水平作为观察指标并反映病情的严重程度。
목적：위료경호적관찰중증폐염환자병정변화정황，분석화연구혈청강개소원화C반응단백재치료과정중적변화정황。방법장2010년5월～2013년5월간래하원시원성구인민의원취진적86례폐염환자근거병정적엄중정도분위관찰조화대조조，기중관찰조환자43례，균위병정진전기중증폐염환자，대조조환자43례위경도폐염환자，대비화분석2조환자치료전후혈청강개소원화C-반응단백수평적개변정황급여예후적관계。결과중증폐염조환자적혈청강개소원화C-반응단백수평현저고우경도폐염조환자，차비교차이구유통계학의의（P<0.05）。결론대우중증폐염환자기병정변화가장혈청강개소원화 C-반응단백수평작위관찰지표병반영병정적엄중정도。
Objective To observe the state changes of severe pneumonia patients better,as well as analyze and study the changes of serum procalcitonin and C-reactive protein during treatment . Methods Divided 86 cases of pneumonia patients treated in our hospital during May 2010 to May 2013 into observation group and control group according to the severity of illness, the patients of observation group(43 cases)were with severe pneumonia the control group, while the control group(43 cases) were with mild pneumonia,compared and discussed the changes and relationships with prognosis of serum procalcitonin and C-reactive protein level before and after treatment in the two groups. Results The serum procalcitonin and C-reactive protein levels of severe pneumonia patients were significantly higher than mild pneumonia patients, and the difference was statistically significant (P<0.05). Conclusion For patients with severe pneumonia,serum procalcitonin and C-reactive protein levels can adopt as observation target and reflect the severity of the disease.