CAJ | 학술논문

目的：了解女性患者解脲脲原体（Ureaplasma urealyticum ，Uu）和人型支原体（Mycoplasma hominis ，Mh）对目前常用具有抗支原体活性抗菌药物的耐药情况。方法采用支原体鉴定药敏试剂盒，对1238例女性疑似泌尿生殖道感染标本进行培养及药敏试验。结果1238份标本中 Uu 阳性492份（39．7％），Uu＋Mh 阳性31份（2．5％），Mh 阳性1份（0．4％），总检出率42．3％（524份）。药敏试验结果显示，Uu 和 Mh 对交沙霉素、多西环素、米诺环素敏感率高，对红霉素、阿奇霉素、氧氟沙星耐药率较高。结论Uu 和 Mh 对常用抗支原体药物耐药率增高，经验治疗应首选交沙霉素、多西环素或米诺环素。
목적：료해녀성환자해뇨뇨원체（Ureaplasma urealyticum ，Uu）화인형지원체（Mycoplasma hominis ，Mh）대목전상용구유항지원체활성항균약물적내약정황。방법채용지원체감정약민시제합，대1238례녀성의사비뇨생식도감염표본진행배양급약민시험。결과1238빈표본중 Uu 양성492빈（39．7％），Uu＋Mh 양성31빈（2．5％），Mh 양성1빈（0．4％），총검출솔42．3％（524빈）。약민시험결과현시，Uu 화 Mh 대교사매소、다서배소、미낙배소민감솔고，대홍매소、아기매소、양불사성내약솔교고。결론Uu 화 Mh 대상용항지원체약물내약솔증고，경험치료응수선교사매소、다서배소혹미낙배소。
Objective To investigate the profile of antimicrobial resistance in theUreaplasma urealyticum (Uu)and Mycoplas-ma hominis (Mh)strains isolated from the female patients suspected of urogenital tract infection.Methods A total of 1 238 specimens were collected from the female patients suspected of urogenital tract infection.Mycoplasma species were identified and tested for their susceptibility with commercial testing kit.Results Of the 1 238 patients,524 (42.3%)cases of Mycoplas-ma were identified,including 492 cases of Uu,31 cases of Uu/Mh mixed infection and 1 case of Mh.The results of antimicro-bial susceptibility testing showed that Uu and Mh isolates were more susceptible to josamycin,doxycycline and minocycline, but relatively resistant to erythromycin,azithromycin and ofloxacin.Conclusions More Uu and Mh isolates from urogenital in-fections are resistant to the commonly used anti-mycoplasma agents.Josamycin,doxycycline or minocycline should be the first choice for empirical treatment of such infections.