CAJ | 학술논문

目的：分析芬兰糖尿病风险评分（FINDRISC）和代谢综合征的相关性。方法以来自江苏徐州地区的1780名社区人群为研究对象，检测受试者甘油三酯（TG）、总胆固醇（TC）、高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇（LDL-C）、空腹血糖（FBG）和餐后2 h血糖（PBG）等相关生化指标。FINDRISC 问卷由专业营养师询问评估，包括年龄、体重指数、腰围、体力活动、饮食习惯、有否高血压或服降压药史、有否血糖升高史和家族糖尿病史。结果用 FINDRISC 来评估代谢综合征的受试者工作曲线下面积为0.78（95%CI 0.76～0.80），其中男性为0.76（95%CI 0.74～0.79），女性为0.80（95%CI 0.75～0.85）。而在最佳诊断截点（FINDRISC=12.5分），诊断代谢综合征的敏感度为70.7%，特异度为74.7%。FINDRISC 与代谢综合发生的风险相关，校正相关参数（年龄、腰围、体重指数、空腹血糖）后，这种相关性依然存在。结论 FINDRISC和代谢综合征密切相关，是一种较为实用的评估代谢综合征的指标。
목적：분석분란당뇨병풍험평분（FINDRISC）화대사종합정적상관성。방법이래자강소서주지구적1780명사구인군위연구대상，검측수시자감유삼지（TG）、총담고순（TC）、고밀도지단백담고순（HDL-C）、저밀도지단백담고순（LDL-C）、공복혈당（FBG）화찬후2 h혈당（PBG）등상관생화지표。FINDRISC 문권유전업영양사순문평고，포괄년령、체중지수、요위、체력활동、음식습관、유부고혈압혹복강압약사、유부혈당승고사화가족당뇨병사。결과용 FINDRISC 래평고대사종합정적수시자공작곡선하면적위0.78（95%CI 0.76～0.80），기중남성위0.76（95%CI 0.74～0.79），녀성위0.80（95%CI 0.75～0.85）。이재최가진단절점（FINDRISC=12.5분），진단대사종합정적민감도위70.7%，특이도위74.7%。FINDRISC 여대사종합발생적풍험상관，교정상관삼수（년령、요위、체중지수、공복혈당）후，저충상관성의연존재。결론 FINDRISC화대사종합정밀절상관，시일충교위실용적평고대사종합정적지표。
Objective To investigate the relationship between the Finnish Diabetes Risk Score(FINDRISC) and Metabolic Syndrome. Methods The study samples were from a community-based health examination survey in Xuzhou, Jiangsu province of China. A total of 1780 subjects were included in the present study. Serum triglyceride(TG), total cholesterol(TC), high density lipoprotein cholesterol(HDL-C), low density lipoprotein cholesterol(LDL-C)and glucose were measured. The FINDRISC questionnaire was applied by registered nutritionists. Points were attributed for the following parameters: age, self-reported use of blood pressure medication, history of high blood glucose, physical activity at least 4h a week, daily consumption of vegetables, fruits, and berries, and measured body mass index (BMI, kg/m2) and waist circumference, and family history of diabetes. Results The area under the receiver operating characteristics curve for steatosis was 0.78 (95% CI 0.76-0.80);0.76 in men (95%CI 0.74-0.79) and 0.80 (95%CI 0.75-0.85) in women. The optimal cutoff value for detecting the Metabolic Syndrome was a FINDRISC greater or equal to 12.5, with sensitivity of 70.7% and specificity of 74.7%. FINDRISC was associated with the risk of Metabolic Syndrome, the associations is still there, after adjust for the following parameters(age, waist circumference, body mass index, fasting blood sugar). Conclusions The FINDRISC was found to be correlated with metabolic syndrome. The FINDRISC is a useful clinical practical evaluation index of metabolic syndrome.