中华医学超声杂志（电子版）
中華醫學超聲雜誌（電子版）
중화의학초성잡지（전자판）
CHINESE JOURNAL OF MEDICAL ULTRASOUND(ELECTRONICAL VISION)
2014年
1期
38-43
,共6页
官勇%李胜利%付倩%涂新枝%罗国阳
官勇%李勝利%付倩%塗新枝%囉國暘
관용%리성리%부천%도신지%라국양
超声检查,产前%胎儿%肺动脉
超聲檢查,產前%胎兒%肺動脈
초성검사,산전%태인%폐동맥
Ultrasonography,prenatal%Fetus%Pulmonary artery
目的：探讨正常胎儿主肺动脉多普勒流速曲线参数测值与孕龄的相关性。方法将孕龄为23~40周的252例正常胎儿按照孕龄分为10组，利用超声多普勒测量胎儿主肺动脉流速曲线参数：收缩期加速时间（AT）、射血时间（ET）、加速时间/射血时间（AT/ET）、收缩期峰值流速（PSV）、舒张期末流速（EDV）、平均流速（MV）、搏动指数（PI）、阻力指数（RI）。建立不同孕龄各流速曲线参数的正常参考值，对各参数与孕龄绘制散点图、进行相关和回归分析，选择最优化方程。结果252例正常胎儿中，胎儿主肺动脉多普勒流速曲线测量成功249例（98.8%，249/252）。胎儿主肺动脉多普勒流速曲线参数测值随孕龄增加的变化：AT、AT/ET、PSV、EDV、MV测值随孕龄增加而呈增大趋势（F=343.23、96.012、8.649、2.158、10.169，P均＜0.05）；PI测值随孕龄增加而呈减小趋势（F=2.346，P＜0.05）；ET、RI随孕龄增加测值无明显变化（F=0.883、1.534，P＞0.05）。AT、AT/ET、PSV、EDV、MV测值与孕龄呈显著线性正相关（r=0.898、0.868、0.446、0.203、0.507， P均＜0.01）；PI测值与孕龄呈显著线性负相关（r=-0.184，P＜0.01）；ET、RI测值与孕龄无相关性（r=-0.103、0.011，P均＞0.05）。结论胎儿主肺动脉为超声多普勒测量肺动脉流速曲线的可靠测量点。正常胎儿主肺动脉流速曲线参数与孕龄有一定相关性，AT、AT/ET与胎儿孕龄相关性最好。
目的：探討正常胎兒主肺動脈多普勒流速麯線參數測值與孕齡的相關性。方法將孕齡為23~40週的252例正常胎兒按照孕齡分為10組，利用超聲多普勒測量胎兒主肺動脈流速麯線參數：收縮期加速時間（AT）、射血時間（ET）、加速時間/射血時間（AT/ET）、收縮期峰值流速（PSV）、舒張期末流速（EDV）、平均流速（MV）、搏動指數（PI）、阻力指數（RI）。建立不同孕齡各流速麯線參數的正常參攷值，對各參數與孕齡繪製散點圖、進行相關和迴歸分析，選擇最優化方程。結果252例正常胎兒中，胎兒主肺動脈多普勒流速麯線測量成功249例（98.8%，249/252）。胎兒主肺動脈多普勒流速麯線參數測值隨孕齡增加的變化：AT、AT/ET、PSV、EDV、MV測值隨孕齡增加而呈增大趨勢（F=343.23、96.012、8.649、2.158、10.169，P均＜0.05）；PI測值隨孕齡增加而呈減小趨勢（F=2.346，P＜0.05）；ET、RI隨孕齡增加測值無明顯變化（F=0.883、1.534，P＞0.05）。AT、AT/ET、PSV、EDV、MV測值與孕齡呈顯著線性正相關（r=0.898、0.868、0.446、0.203、0.507， P均＜0.01）；PI測值與孕齡呈顯著線性負相關（r=-0.184，P＜0.01）；ET、RI測值與孕齡無相關性（r=-0.103、0.011，P均＞0.05）。結論胎兒主肺動脈為超聲多普勒測量肺動脈流速麯線的可靠測量點。正常胎兒主肺動脈流速麯線參數與孕齡有一定相關性，AT、AT/ET與胎兒孕齡相關性最好。
목적：탐토정상태인주폐동맥다보륵류속곡선삼수측치여잉령적상관성。방법장잉령위23~40주적252례정상태인안조잉령분위10조，이용초성다보륵측량태인주폐동맥류속곡선삼수：수축기가속시간（AT）、사혈시간（ET）、가속시간/사혈시간（AT/ET）、수축기봉치류속（PSV）、서장기말류속（EDV）、평균류속（MV）、박동지수（PI）、조력지수（RI）。건립불동잉령각류속곡선삼수적정상삼고치，대각삼수여잉령회제산점도、진행상관화회귀분석，선택최우화방정。결과252례정상태인중，태인주폐동맥다보륵류속곡선측량성공249례（98.8%，249/252）。태인주폐동맥다보륵류속곡선삼수측치수잉령증가적변화：AT、AT/ET、PSV、EDV、MV측치수잉령증가이정증대추세（F=343.23、96.012、8.649、2.158、10.169，P균＜0.05）；PI측치수잉령증가이정감소추세（F=2.346，P＜0.05）；ET、RI수잉령증가측치무명현변화（F=0.883、1.534，P＞0.05）。AT、AT/ET、PSV、EDV、MV측치여잉령정현저선성정상관（r=0.898、0.868、0.446、0.203、0.507， P균＜0.01）；PI측치여잉령정현저선성부상관（r=-0.184，P＜0.01）；ET、RI측치여잉령무상관성（r=-0.103、0.011，P균＞0.05）。결론태인주폐동맥위초성다보륵측량폐동맥류속곡선적가고측량점。정상태인주폐동맥류속곡선삼수여잉령유일정상관성，AT、AT/ET여태인잉령상관성최호。
Objective To explore the correlations between measurements of Doppler velocity waveform parameters of fetal main pulmonary artery and gestation age (GA) in normal fetus. Methods This is a cross-sectional study, in which totally 252 normal singleton fetuses between 23 and 40 weeks of gestation were divided into 10 groups. The following velocity waveform parameters were measured in the main trunk of fetal pulmonary artery by Doppler ultrasound: acceleration time(AT), ejection time(ET), acceleration time/ejection time(AT/ET), peak systolic velocity(PSV), end diastolic velocity(EDV), mean velocity(MV), pulsatility index(PI) and resistance index(RI). The normal reference values of Doppler velocity waveform parameters at various GA were established. A scatter diagram of each parameter against GA was plotted out. The optimal formula was selected out according to the correlation and regression analysis. Results Among 252 normal fetuses, satisfactory Doppler velocity waveform of fetal main pulmonary were achieved in 249 (98.8%, 249/252). Among these parameters, AT, AT/ET, PSV, EDV and MV increased with increasing GA(F=343.23, 96.012, 8.649, 2.158, 10.169, all P<0.05), while PI decreased slightly(F=2.346, P<0.05) and ET, RI had no signiifcant changing(F=0.883, 1.534, both P>0.05). Signiifcant and positive linear correlations were found between parameters of AT, AT/ET, PSV, EDV, MV and GA(r= 0.898, 0.868, 0.446, 0.203, 0.507, all P<0.01);while PI was inversely linear correlated with GA(r=-0.184, P<0.01) and ET, RI had no correlation with GA(r=-0.103, 0.011, both P>0.05). Conclusions The fetal main pulmonary artery could be a reliable sampling point to obtain pulmonary velocity waveform by Doppler ultrasound. Doppler velocity waveform parameters have correlations with GA in normal fetus;among which AT and AT/ET were the best.
