世界最新医学信息文摘（电子版）
世界最新醫學信息文摘（電子版）
세계최신의학신식문적（전자판）
World Latest Medicine Information
2014年
2期
36-37,43
,共3页
新生儿呼吸窘迫综合征%持续气道正压通气%气管插管%早产儿
新生兒呼吸窘迫綜閤徵%持續氣道正壓通氣%氣管插管%早產兒
신생인호흡군박종합정%지속기도정압통기%기관삽관%조산인
nrds%cPaP%endotracheal intubation%premature infants
在提倡减少肺损伤的时代，持续气道正压通气(continuous positive airway pressure ，cPaP)作为无创通气技术近年来已经被证实有效，因此，其对新生儿呼吸系统疾病，尤其是新生儿呼吸窘迫综合征（respiratory distress syndrome ，rds)的治疗在全世界范围得到推广。此外，cPaP 便宜、操作简便、易于在发展中国家实施。有研究证实 cPaP可以减少早产儿的气管插管及机械通气，故可避免呼吸机相关性肺损伤及降低支气管肺发育不良（bronchopulmonary dysplasia，BPd)，且证实其甚至对极低体重出生儿 rds 有效。本文就 cPaP 对早产儿 rds 的不同应用方式做一简单综述， cPaP 的其它优点也将简单阐述。虽然，cPaP 是否能减轻所有新生儿的发病率和死亡率仍未知，但是越来越明确的是早期应用 cPaP 对患儿创伤少，并可减少对肺表面活性物质的需要。
在提倡減少肺損傷的時代，持續氣道正壓通氣(continuous positive airway pressure ，cPaP)作為無創通氣技術近年來已經被證實有效，因此，其對新生兒呼吸繫統疾病，尤其是新生兒呼吸窘迫綜閤徵（respiratory distress syndrome ，rds)的治療在全世界範圍得到推廣。此外，cPaP 便宜、操作簡便、易于在髮展中國傢實施。有研究證實 cPaP可以減少早產兒的氣管插管及機械通氣，故可避免呼吸機相關性肺損傷及降低支氣管肺髮育不良（bronchopulmonary dysplasia，BPd)，且證實其甚至對極低體重齣生兒 rds 有效。本文就 cPaP 對早產兒 rds 的不同應用方式做一簡單綜述， cPaP 的其它優點也將簡單闡述。雖然，cPaP 是否能減輕所有新生兒的髮病率和死亡率仍未知，但是越來越明確的是早期應用 cPaP 對患兒創傷少，併可減少對肺錶麵活性物質的需要。
재제창감소폐손상적시대，지속기도정압통기(continuous positive airway pressure ，cPaP)작위무창통기기술근년래이경피증실유효，인차，기대신생인호흡계통질병，우기시신생인호흡군박종합정（respiratory distress syndrome ，rds)적치료재전세계범위득도추엄。차외，cPaP 편의、조작간편、역우재발전중국가실시。유연구증실 cPaP가이감소조산인적기관삽관급궤계통기，고가피면호흡궤상관성폐손상급강저지기관폐발육불량（bronchopulmonary dysplasia，BPd)，차증실기심지대겁저체중출생인 rds 유효。본문취 cPaP 대조산인 rds 적불동응용방식주일간단종술， cPaP 적기타우점야장간단천술。수연，cPaP 시부능감경소유신생인적발병솔화사망솔잉미지，단시월래월명학적시조기응용 cPaP 대환인창상소，병가감소대폐표면활성물질적수요。
in the era of gentle ventilation ,continuous positive airway pressure (cPaP) has been proven over the years to be an effective mode of noninvasive ventilatory support and as such has gained widespread use around the world in the management of a variety of neonatal respiratory diseases, particulary respiratory distress syndrome (rds).it is relatively cheap and easy to apply and certainly feasible for routine use in underdeveloped world.there is good to fair quality supportive evidence from several studies that the use of primary cPaP can reduce the need for intubation and mechanical ventilation in premature infants and could avoid ventilator induced lung injury and decrease bronchopulmonary dysplasia(BPd).cPaP has also been shown to be effective in the treatment of respiratory distress syndrome (rds) even in very low birth weight infants. in this review, we will attempt to describe different ways in which cPaP can be applied,other advantages of clinical indications for cPaP will also be explored. although it is unclear that primary use of cPaP can reduce overall neonatal mortality and morbidity ,it is becoming increasingly clear that early cPaP use is less invasive baby friendly and decreases the need and frequency of the use of surfactants.
