中国实用医药
中國實用醫藥
중국실용의약
CHINA PRACTICAL MEDICAL
2014年
7期
7-8
,共2页
心绞痛%不稳定型%肌钙蛋白T%心血管造影术%预后
心絞痛%不穩定型%肌鈣蛋白T%心血管造影術%預後
심교통%불은정형%기개단백T%심혈관조영술%예후
Angina%Unstable%Troponin T%Angiography%Prognosis
目的：探讨不稳定型心绞痛(UAP)患者高敏肌钙蛋白T(hs-cTnT)水平与冠状动脉病变及预后的关系。方法156例UAP住院患者常规测定hs-cTnT水平,根据hs-cTnT水平分为hs-cTnT阳性组(44例),阴性组(112例)。住院期间行冠状动脉造影(CAG)检查,随访30 d,记录心血管不良事件。结果 hs-cTnT阳性组冠脉造影阳性率93.2%,三支病变的发生率37.7%,冠状动脉内血栓发生率18.2%,均明显高于阴性组；hs-cTnT阳性组hs-cTnT水平随着冠脉病变的严重程度而升高,30 d内总的心脏事件发生率(25%),明显高于hs-cTnT阴性组(5.5%),两组相比差异有统计学意义(P<0.01)。结论 hs-cTnT水平的高低可预测UAP患者冠脉病变的严重程度及其病变范围,其升高提示短期预后不良,主要心血管事件发生率增加,可作为UAP早期危险分层的指标,对指导治疗亦有重要意义。
目的：探討不穩定型心絞痛(UAP)患者高敏肌鈣蛋白T(hs-cTnT)水平與冠狀動脈病變及預後的關繫。方法156例UAP住院患者常規測定hs-cTnT水平,根據hs-cTnT水平分為hs-cTnT暘性組(44例),陰性組(112例)。住院期間行冠狀動脈造影(CAG)檢查,隨訪30 d,記錄心血管不良事件。結果 hs-cTnT暘性組冠脈造影暘性率93.2%,三支病變的髮生率37.7%,冠狀動脈內血栓髮生率18.2%,均明顯高于陰性組；hs-cTnT暘性組hs-cTnT水平隨著冠脈病變的嚴重程度而升高,30 d內總的心髒事件髮生率(25%),明顯高于hs-cTnT陰性組(5.5%),兩組相比差異有統計學意義(P<0.01)。結論 hs-cTnT水平的高低可預測UAP患者冠脈病變的嚴重程度及其病變範圍,其升高提示短期預後不良,主要心血管事件髮生率增加,可作為UAP早期危險分層的指標,對指導治療亦有重要意義。
목적：탐토불은정형심교통(UAP)환자고민기개단백T(hs-cTnT)수평여관상동맥병변급예후적관계。방법156례UAP주원환자상규측정hs-cTnT수평,근거hs-cTnT수평분위hs-cTnT양성조(44례),음성조(112례)。주원기간행관상동맥조영(CAG)검사,수방30 d,기록심혈관불량사건。결과 hs-cTnT양성조관맥조영양성솔93.2%,삼지병변적발생솔37.7%,관상동맥내혈전발생솔18.2%,균명현고우음성조；hs-cTnT양성조hs-cTnT수평수착관맥병변적엄중정도이승고,30 d내총적심장사건발생솔(25%),명현고우hs-cTnT음성조(5.5%),량조상비차이유통계학의의(P<0.01)。결론 hs-cTnT수평적고저가예측UAP환자관맥병변적엄중정도급기병변범위,기승고제시단기예후불량,주요심혈관사건발생솔증가,가작위UAP조기위험분층적지표,대지도치료역유중요의의。
Objective To investigate the relationship between high-sensitivity troponin T and the severity of coronary artery and prognosis in patients with coronary artery disease. Methods The level of hs-cTnT of 156 hospitalized patients with UAP was determined routinely. The patients were divided into hs-cTnT-positive group (44 cases) and negative group (112 cases) according to the level of hs-cTnT. During hospitalization, all of the patients underwent coronary angiography (CAG), after discharge, they were followed for 30 days,and cardiovascular adverse events were recorded. Results The positive rate of coronary angiography was 93.2%in hs-cTnT positive group, and the incidence of three-vessel disease was 37.7%, the incidence of coronary thrombosis was 18.2%, and all of them were significantly higher than the negative group. In the hs-cTnT positive group, the level of hs-cTnT increased with the severity of coronary artery disease, the rate of 30-days-total-cardiac-event was 25%, and was significantly higher than the hs-cTnT negative group (5.5%), the difference was statistically significant (P<0.01). Conclusion The level of hs-cTnT can predict the severity of coronary artery disease in patients with UAP, the elevated prompt poor short-term prognosis, increased risk of major cardiovascular events, hs-cTnT levels can be used as indicators of the UAPearly risk stratification, to guidetreatment also of great significance.
