CAJ | 학술논문

目的：应用脉冲多普勒测量心室Tei指数，探讨母体高血压环境对胎儿心功能的影响及其出生后的心功能状况。方法选择孕28～41＋6周的胎儿185例，产后1～7 d的新生儿203例，产后4～5个月婴儿174例。胎儿、新生儿及婴儿均设对照组和研究组，研究组分为妊娠期高血压（ GH）组、轻度子痫前期（ MPE）组、重度子痫前期（ SPE）组。对所有研究对象进行左右心室Tei指数的测量并进行比较。结果 GH组与对照组胎儿左右心室Tei指数比较差异无统计学意义；MPE组、SPE组胎儿左右心室Tei指数大于对照组胎儿（ P均＜0.05）。 GH组、MPE组、SPE组足月产与对照组足月产新生儿比较，左右心室Tei指数无显著性差异。对照组早产与对照组足月产新生儿左右心室Tei指数比较无显著性差异。 SPE组早产、MPE组早产新生儿左右心室Tei指数均大于对照组足月产新生儿（P均＜0．05）。 GH组、MPE组、SPE组足月产4～5个月婴儿与对照组足月产4～5个月婴儿比较，左右心室Tei指数无显著性差异。 SPE组、MPE组及对照组早产4～5个月婴儿与对照组足月产4～5个月婴儿比较，左右心室Tei指数无显著性差异。结论子痫前期胎儿左、右心室整体功能均受损害；单纯的早产因素并不引起新生儿心功能的改变；子痫前期胎儿在生后4～5个月内Tei指数均恢复正常水平。
목적：응용맥충다보륵측량심실Tei지수，탐토모체고혈압배경대태인심공능적영향급기출생후적심공능상황。방법선택잉28～41＋6주적태인185례，산후1～7 d적신생인203례，산후4～5개월영인174례。태인、신생인급영인균설대조조화연구조，연구조분위임신기고혈압（ GH）조、경도자간전기（ MPE）조、중도자간전기（ SPE）조。대소유연구대상진행좌우심실Tei지수적측량병진행비교。결과 GH조여대조조태인좌우심실Tei지수비교차이무통계학의의；MPE조、SPE조태인좌우심실Tei지수대우대조조태인（ P균＜0.05）。 GH조、MPE조、SPE조족월산여대조조족월산신생인비교，좌우심실Tei지수무현저성차이。대조조조산여대조조족월산신생인좌우심실Tei지수비교무현저성차이。 SPE조조산、MPE조조산신생인좌우심실Tei지수균대우대조조족월산신생인（P균＜0．05）。 GH조、MPE조、SPE조족월산4～5개월영인여대조조족월산4～5개월영인비교，좌우심실Tei지수무현저성차이。 SPE조、MPE조급대조조조산4～5개월영인여대조조족월산4～5개월영인비교，좌우심실Tei지수무현저성차이。결론자간전기태인좌、우심실정체공능균수손해；단순적조산인소병불인기신생인심공능적개변；자간전기태인재생후4～5개월내Tei지수균회복정상수평。
Objective It is to explore the influence of maternal hypertension environment on cardiac function of fetus and neonate evaluated with ventricular Tei index by pulsed Doppler .Methods 185 cases of 28 weeks to 41 weeks and 6 days old fetuses,203 cases of 1-7 days old neonates and 174 cases of 4-5 months old infants were selected .Fetus, neonatal and in-fants were divided into control group and study group .The study groups were divided into gestational hypertension ( GH ) group, mild preeclampsia (MPE) group and severe preeclampsia (SPE) group.The left and right ventricle Tei index of each case was examined and compared .Results Compare the left and right ventricular Tei index of GH group with the control group, there was no statistically significant difference (P>0.05), but the indexes in MPE group and SPE group were higher than that of the control group (P<0.05).Compare the left and right ventricular Tei index of full-term neonate in GH group, MPE group, SPE group with control group, there were no statistical significance (P>0.05).Compare the left and right ven-tricular Tei index of preterm neonate group with full-term neonates in control group , the differences was not statistically signifi-cant (P>0.05).Left and right ventricular Tei indexes of premature neonatal in SPE group and MPE group were greater than full-term neonate in control group, the differences was statistical significant (P<0.05).Compare left and right ventricular Tei index of 4-5 months old full-term infant in GH group, MPE group, SPE group with 4-5 months old full-term infant in con-trol group, there was no statistical significant difference (P>0.05).The differences of left and right ventricular Tei index be-tween 4-5 months old preterm infants in SPE group , MPE group and 4-5 months old full-term infants in control groups were not statistical significant (P>0.05).Conclusion In preeclampsia, left and right ventricular overall function of fetal was dam-aged.Only premature can’t cause the change of neonatal cardiac function .For preeclampsia fetus, Tei index will be recov-ered to the normal level within 4-5 months old ( post-birth) .