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化学研究与应用 화학연구여응용
CHEMICAL RESEARCH AND APPLICATION
2014年 2期 286-289 ,共4页

王力%何玉玲%周雨杨%刘晓燕%韦思平%首平平%王琳%杜曦%王钦

왕력%하옥령%주우양%류효연%위사평%수평평%왕림%두희%왕흠

手性炔醇%醛%BINOL/Ti(OiPr)4%不对称加成反应手性炔醇%醛%BINOL/Ti(OiPr)4%不對稱加成反應
수성결순%철%BINOL/Ti(OiPr)4%불대칭가성반응
chiral propargylic alcohol%aldehyde%BINOL/Ti(O i Pr) 4%asymmetric addition

利用手性联二萘酚/Ti（O i Pr）4配合物作为催化剂，对辛炔对醛的不对称加成反应进行了研究。在该体系下，芳香醛、脂肪醛以及α，β-不饱和醛类底物都可通过该方法获取相应手性炔醇产物，并可取得中等至良好的对映选择性。
이용수성련이내분/Ti（O i Pr）4배합물작위최화제，대신결대철적불대칭가성반응진행료연구。재해체계하，방향철、지방철이급α，β-불포화철류저물도가통과해방법획취상응수성결순산물，병가취득중등지량호적대영선택성。
A follow-up research on the construction of optically active propargylic alcohols by the BINOL /Ti(Oi Pr)4 catalyzed asym-metric addition of alkynylzinc reagents to aldehydes had been presented.Besides simple aromatic aldehyde substrate ,α,β-unsaturat-ed aldehyde and aliphatic aldehyde substrates were also involved in this work.