CAJ | 학술논문

以马铃薯淀粉和黄原胶为单体制备得到了淀粉黄原胶交联膜，运用红外光谱、扫描电子显微镜、热重分析手段对产物进行了表征；以亚甲基蓝为模型药物，研究了交联膜在两种不同介质中时间、温度、药液浓度对其载药性能的影响；实验结果表明：淀粉与黄原胶都与交联剂发生了反应形成了交联膜，膜表面光滑，有较高耐热性，在pH＝7.4的PBS中的载药性能优于在0.9％的生理盐水中的载药性能，且在这两种介质中载药趋势相同，都在30min，35℃时的条件下有较好的载药性。
이마령서정분화황원효위단체제비득도료정분황원효교련막，운용홍외광보、소묘전자현미경、열중분석수단대산물진행료표정；이아갑기람위모형약물，연구료교련막재량충불동개질중시간、온도、약액농도대기재약성능적영향；실험결과표명：정분여황원효도여교련제발생료반응형성료교련막，막표면광활，유교고내열성，재pH＝7.4적PBS중적재약성능우우재0.9％적생리염수중적재약성능，차재저량충개질중재약추세상동，도재30min，35℃시적조건하유교호적재약성。
Cross-linked starch-xanthan gum film was prepared,the reaction product was characterized using FTIR ,scanning electron microscopy and thermal gravimetric analysis .The effect of loading time,temperature and drug concentration on the film's drug load-ing performance were investigated.The results showed that the new prepared starch-xanthan gum film had smooth surface and high heat resistance,and had the better drug loading performance under the condition of 35℃and 30 min of loading time in the medium of PBS at pH=7.4 than in the 0.9%saline.