CAJ | 학술논문

目的：研究“益气化积”方对晚期肿瘤的治疗作用。方法：采用随机、对照方法，将55例晚期肿瘤患者分为治疗组29例、对照组26例，观察2组患者治疗前后KPS评分、体重、近期客观疗效、免疫、凝血等指标。结果：治疗组KPS评分和体重均高于对照组，差异有统计学意义（P﹤0.05）。治疗组CD3、CD4、CD4/CD8升高，CD8下降，治疗前后比较有显著性差异（P﹤0.05），与对照组比较无显著性差异（P﹥0.05）；治疗组Fib、PT均明显下降（P﹤0.05），与对照组比较无显著性差异（P﹥0.05）；治疗组近期有效率为31.03%，高于对照组19.23%，两组比较无显著性差异（P﹥0.05）。结论：“益气化积”方能显著提高晚期肿瘤患者的KPS评分和体重，改善免疫、凝血指标，可一定程度地抑制肿瘤进展。
목적：연구“익기화적”방대만기종류적치료작용。방법：채용수궤、대조방법，장55례만기종류환자분위치료조29례、대조조26례，관찰2조환자치료전후KPS평분、체중、근기객관료효、면역、응혈등지표。결과：치료조KPS평분화체중균고우대조조，차이유통계학의의（P﹤0.05）。치료조CD3、CD4、CD4/CD8승고，CD8하강，치료전후비교유현저성차이（P﹤0.05），여대조조비교무현저성차이（P﹥0.05）；치료조Fib、PT균명현하강（P﹤0.05），여대조조비교무현저성차이（P﹥0.05）；치료조근기유효솔위31.03%，고우대조조19.23%，량조비교무현저성차이（P﹥0.05）。결론：“익기화적”방능현저제고만기종류환자적KPS평분화체중，개선면역、응혈지표，가일정정도지억제종류진전。
Objective:To study therapeutic effects of qi-tonifying and mass-eliminating prescriptions to advanced cancer. Methods:55 cases of advanced cancer were randomly divided into two groups, treatment group of 29 cases and control group of 26 cases;and we observed KPS scores, weight, short-term effects, immunity and coagulation etc. indicators of the two groups. Results: KPS scores and weight of the treatment group were higher than those of the control group, the difference being statistically significant (P<0.05). CD3, CD4 and CD4/CD8 of the treatment group increased while CD8 decreased. The differences between before and after the treatment were statistically significant (P<0.05) while compared with the control group there was no significant difference (P>0.05). Both Fib and PT decreased significantly of the treatment group (P<0.05), and there was no significant difference from the control group. Short-term efficiency of the treatment group was 31.03%, which was higher than that of the control group of 19.23%, and the difference was not statistically different (P>0.05). Conclusion:Qi-tonifying and mass-eliminating prescriptions can significantly improve KPS scores, weight, immunity and coagulation indicators of advanced cancer patients, and can control cancer progression to some extent.