CAJ | 학술논문

目的：探讨艾滋病合并口腔念珠菌病的临床特点和诊治转归。方法：回顾性研究从2012-09～2013-03北京地坛医院收治的31例艾滋病合并口腔念珠菌感染者的临床资料，包括一般资料、临床特征、口腔表现、CD4细胞计数、机会性感染状况、抗真菌治疗转归等。结果：31例患者中30例 CD4细胞计数小于200个/μl，有29例合并多种机会性感染。临床表现30例为假膜型，1例为红斑型，2例假膜型合并口角炎型。抗真菌治疗后，8例病损缩小，23例病损完全消失，3例停药后复发。结论：艾滋病合并口腔念珠菌病临床上多见于 CD4细胞＜200个/μl 的患者，临床表现以假膜型为主，常合并有其他部位的多种机会性感染。这类患者抗真菌治疗有效。
목적：탐토애자병합병구강념주균병적림상특점화진치전귀。방법：회고성연구종2012-09～2013-03북경지단의원수치적31례애자병합병구강념주균감염자적림상자료，포괄일반자료、림상특정、구강표현、CD4세포계수、궤회성감염상황、항진균치료전귀등。결과：31례환자중30례 CD4세포계수소우200개/μl，유29례합병다충궤회성감염。림상표현30례위가막형，1례위홍반형，2례가막형합병구각염형。항진균치료후，8례병손축소，23례병손완전소실，3례정약후복발。결론：애자병합병구강념주균병림상상다견우 CD4세포＜200개/μl 적환자，림상표현이가막형위주，상합병유기타부위적다충궤회성감염。저류환자항진균치료유효。
Objective:To study the clinical features and treatment outcome of AIDS associated oral candidiasis.Methods:The clinical data of 31 cases with AIDSassociated oral candidiasis from 201209 to 201303 were studied retrospectively,including general data,clinical features,oral manifestation,CD4 cell count,opportunistic infections,and antifungal therapy outcome,etc.Results:CD4cell count <200 cell/μl was found in 30 cases,AIDSrelated multiple opportunistic infection was observed in 29 cases.30 cases hadpseudomembranous candidiasis,1 cases had erythematous candidiasis and 2 cases had pseudomembranous candidiasis with angular candidiasis.After antifungal treatment,the lesion of 8 cases reduced,that of 23 cases disappeared completely,lesion relapse after drugwithdrawal happened in 3 cases.Conclusion:AIDSassociated oral candidiasis was more common in AIDS patients with CD4 <200cells/μl,the main clinical form is pseudomembranous type,and with multiple opportunistic infections.The antifungal treatment is effective for the patients.