CAJ | 학술논문

目的：总结分析呼吸道感染住院患儿的痰培养结果，了解引起呼吸道感染病原谱及药敏情况变化，为呼吸道感染治疗用药指导提供一定参考依据。方法：2010年1月-2012年12月收治呼吸道感染患儿381例，回顾分析其痰培养结果和主要病原菌耐药性。结果：381例患者中，以肺炎克雷伯杆菌、大肠埃希氏菌、阴沟肠杆菌、鲍曼不动杆菌为主，且肺炎克雷伯杆菌比例(28.61%)及大肠埃希氏菌比例(20.21%)均明显高于其他类病原菌，差异具有统计学意义(P＜0.05)。381例患儿中，共分离出79株耐药菌株，耐药率20.73%，主要为肺炎克雷伯杆菌及大肠埃希氏菌。结论：呼吸道感染病原菌种类分布广泛，革兰阳性菌株较多，为提高临床疗效，必须要合理使用抗生素。
목적：총결분석호흡도감염주원환인적담배양결과，료해인기호흡도감염병원보급약민정황변화，위호흡도감염치료용약지도제공일정삼고의거。방법：2010년1월-2012년12월수치호흡도감염환인381례，회고분석기담배양결과화주요병원균내약성。결과：381례환자중，이폐염극뢰백간균、대장애희씨균、음구장간균、포만불동간균위주，차폐염극뢰백간균비례(28.61%)급대장애희씨균비례(20.21%)균명현고우기타류병원균，차이구유통계학의의(P＜0.05)。381례환인중，공분리출79주내약균주，내약솔20.73%，주요위폐염극뢰백간균급대장애희씨균。결론：호흡도감염병원균충류분포엄범，혁란양성균주교다，위제고림상료효，필수요합리사용항생소。
Objective:Summarize and analyze the sputum culture results of hospitalized children with respiratory infection,to understand the pathogen spectrum of respiratory infection and drug sensitivity changes,and to provide some references for the treatment of respiratory infection.Methods:381 children with respiratory tract infection were selected from January 2010 to December 2012.We retrospectively analyzed the results of sputum culture and drug resistance of pathogens.Results:In 381 cases, the major pathogen were klebsiella pneumoniae,escherichia coli,enterobacter cloacae,bauman acinetobacter.Moreover,klebsiella pneumoniae ratio of 28.61% and escherichia coli ratio of 20.21% were significantly higher than those of other pathogens.The difference was statistically significant(P<0.05).In 381 cases,there were 79 strains of drug-resistant strains,and drug resistance rate was 20.73% .They were mainly klebsiella pneumoniae and escherichia coli.Conclusion:Species of pathogen in respiratory infection are widespread.The strain gram positive is more.In order to improve the clinical efficacy,we must use the antibiotics reasonablely.