CAJ | 학술논문

目的探讨术前放化疗对局部晚期胃癌患者病理降期的效果.方法回顾性分析2009年1月至2013年1月在我院接受治疗的35例局部晚期胃癌患者的临床资料,观察其放化疗方法及病理降期、毒副反应、手术切除等相关情况.结果 35例患者放化疗后有效率为54.29％,疾病控制率为80.00％,降期率为54.29％;手术切除率为88.57％,其不良反应主要以骨髓抑制及胃肠道反应为主.结论术前放化疗可降低局部晚期胃癌患者肿瘤分期,对提高手术切除率、改善预后有积极意义.
목적 탐토술전방화료대국부만기위암환자병리강기적효과.방법 회고성분석2009년1월지2013년1월재아원접수치료적35례국부만기위암환자적림상자료,관찰기방화료방법급병리강기、독부반응、수술절제등상관정황.결과 35례환자방화료후유효솔위54.29％,질병공제솔위80.00％,강기솔위54.29％;수술절제솔위88.57％,기불량반응주요이골수억제급위장도반응위주.결론 술전방화료가강저국부만기위암환자종류분기,대제고수술절제솔、개선예후유적겁의의.
Objective To investigate the down-staging effects of pre-operative chemoradiotherapy in the treatment of locally advanced gastric cancer.Methods Retrospectively analyzed clinical data about 35 cases of locally advanced gastric cancer in our hospital from January 2009 to January 2013.Observed chemoradiotherapy methods,pathological down-staging,toxicity and exairesis.Results The effective rate of chemoradiotherapy in 35 cases was 54.29％,the disease control rate (DCR) was 80.00％,the down-staging rate was 54.29％,and the resection rate was 88.57％.Adverse reactions mainly focused on myelosuppression and gastrointestinal reactions.Conclusion Pre-operative chemoradiotherapy can reduce neoplasm staging of locally advanced gastric cancer,and is effective in improving the resection rate and prognosis.