中南民族大学学报(自然科学版)
中南民族大學學報(自然科學版)
중남민족대학학보(자연과학판)
JOURNAL OF SOUTH-CENTRAL UNIVERSITY FOR NATIONALITIES(NATURAL SCIENCE EDITION)
2013年
3期
26-29
,共4页
刘庆华%马云飞%罗小静%张婷
劉慶華%馬雲飛%囉小靜%張婷
류경화%마운비%라소정%장정
胚胎干细胞%分化%心肌细胞%中药
胚胎榦細胞%分化%心肌細胞%中藥
배태간세포%분화%심기세포%중약
embryonic stem cells%differentiation%cardiomyocytes%Chinese medicine
指出了胚胎干细胞( ES细胞)是一类可进行自我复制和更新并向骨骼、软骨、脂肪、神经、肌肉等多个胚层的组织分化的细胞。研究表明:ES细胞移植入缺血心脏后可以分化形成新生心肌细胞,血管内皮细胞等,还可以通过分泌多种生长因子,促进微循环的建立,提高梗死后心脏功能。综述了中药如黄芩苷、葛根素、淫羊藿苷、黄芪、丹参、皂苷、双龙方等诱导小鼠干细胞分化为心肌细胞的研究进展。
指齣瞭胚胎榦細胞( ES細胞)是一類可進行自我複製和更新併嚮骨骼、軟骨、脂肪、神經、肌肉等多箇胚層的組織分化的細胞。研究錶明:ES細胞移植入缺血心髒後可以分化形成新生心肌細胞,血管內皮細胞等,還可以通過分泌多種生長因子,促進微循環的建立,提高梗死後心髒功能。綜述瞭中藥如黃芩苷、葛根素、淫羊藿苷、黃芪、丹參、皂苷、雙龍方等誘導小鼠榦細胞分化為心肌細胞的研究進展。
지출료배태간세포( ES세포)시일류가진행자아복제화경신병향골격、연골、지방、신경、기육등다개배층적조직분화적세포。연구표명:ES세포이식입결혈심장후가이분화형성신생심기세포,혈관내피세포등,환가이통과분비다충생장인자,촉진미순배적건립,제고경사후심장공능。종술료중약여황금감、갈근소、음양곽감、황기、단삼、조감、쌍룡방등유도소서간세포분화위심기세포적연구진전。
Embryonic stem cells ( ES cells ) are capable of self-replication and renewal .They can differentiate into multiple cell lineages , such as osteoblast , chondrocyte , adipocyte , neurocyte , and muscle cells .Studies have shown that ES cells transplanted into the ischemic heart can regenerate new cells to replace the necrotic cardiomyocytes and vascular endothelial cells .They can also secrete various growth factors to promote a micro-circulation beneficial to the recovery of infarctus heart .Here we reviewed the research on the differentiation of cardiomyocytes from mouse ES cells promoted by some traditional Chinese medicine such as Baicalin , Puerarin, Icariin, Astragalus, Salvia Miltiorrhizas Bge., Saponins, Shuanglong prescription, etc.