CAJ | 학술논문

目的：利用我国青少年锁骨胸骨端骨骺发育变化规律，探讨CT容积再现（volume rendering，VR）数据与生物学年龄的相关性，并建立推断骨龄的数学模型。方法通过对我国华东、华南地区684名15～25周岁青少年双侧锁骨胸骨端进行CT薄层扫描并VR三维图像重组，测量并计算双侧锁骨胸骨端骨骺最长径、干骺端最长径及其长度比、骨骺面积、干骺端面积及其面积比等数据，并建立骨龄推断的数学模型。再将50例训练样本代入数学模型，检验模型的准确性。结果左、右两侧骨骺与干骺端长度比、面积比在同一年龄组男女性间差异具有统计学意义（P<0.05）。建立的数学模型表明锁骨胸骨端骨骼的发育规律与生物学年龄具有高度的相关性，所有模型的准确率都高于70.5%（±1.0岁）和82.5%（±1.5岁）。结论建立的骨龄数学模型的可操作性强、准确性较高。这不仅可与图谱法相互印证和支持，提高骨龄推断的准确性；同时，该方法对未来研究其他单一部位骨龄推断具有重要的意义。
목적：이용아국청소년쇄골흉골단골후발육변화규률，탐토CT용적재현（volume rendering，VR）수거여생물학년령적상관성，병건립추단골령적수학모형。방법통과대아국화동、화남지구684명15～25주세청소년쌍측쇄골흉골단진행CT박층소묘병VR삼유도상중조，측량병계산쌍측쇄골흉골단골후최장경、간후단최장경급기장도비、골후면적、간후단면적급기면적비등수거，병건립골령추단적수학모형。재장50례훈련양본대입수학모형，검험모형적준학성。결과좌、우량측골후여간후단장도비、면적비재동일년령조남녀성간차이구유통계학의의（P<0.05）。건립적수학모형표명쇄골흉골단골격적발육규률여생물학년령구유고도적상관성，소유모형적준학솔도고우70.5%（±1.0세）화82.5%（±1.5세）。결론건립적골령수학모형적가조작성강、준학성교고。저불부가여도보법상호인증화지지，제고골령추단적준학성；동시，해방법대미래연구기타단일부위골령추단구유중요적의의。
Objective To explore the correlation between CTvolume rendering (VR) statistics and living age and to build the mathematical models for skeletal age evaluation based on the grow th rules of medi-al clavicular epiphysis of teenagers in China. Methods The thin layer CTscan and VR3D imaging re-construction of both sides of sternal ends of clavicles were exam ined for 684 teenagers aged from 15 to 25 in East and South China. The parameters of sternal end of clavicle including the longest diameter of epiphysis, the longest diameter of metaphysis, their length radio, area of epiphysis, area of meta-physic, their area ratio, and other data were measured and calculated in order to establish mathematical models of skeletal age evaluation. Fifty trained subjects were tested to verify the accuracy of the math-ematical models. Results In the same age group, the length ratio and the area ratio had significant dif-ference in genders (P<0.05). The established mathematical models showed that the grow th rules of medial clavicular epiphysis were highly correlated with the living ages. The accuracies of these models were higher than 70.5% (±1.0 year) and 82.5% (±1.5 year). Conclusion The mathematical models have easy operability and high accuracy. It can be used to confirmand sustain the conclusion of atlas method. M eanw hile, it is of great significance to study the other single skeletal age evaluation in the future.