中外女性健康（下半月）
中外女性健康（下半月）
중외녀성건강（하반월）
CHINESE-FOREIGN WOMEN'S HEALTH
2013年
6期
66-67,88
,共3页
何琳琳%李洁%朱瑞芳%朱湘玉%张颖%史逸燕
何琳琳%李潔%硃瑞芳%硃湘玉%張穎%史逸燕
하림림%리길%주서방%주상옥%장영%사일연
染色体多态性%不良生殖效应%细胞遗传学
染色體多態性%不良生殖效應%細胞遺傳學
염색체다태성%불량생식효응%세포유전학
Chromosome polymorphism%Abnormal reproductive effect%Cytogenetics
目的：研究染色体多态性与不良临床生殖效应之间的关系。方法：常规外周血淋巴细胞培养，制片，G、C、N显带，核型分析。结果：2660例病人中检出染色体变异141例，其中多态性变异为58例，分别包括D、G组短臂或随体区延长15例，占10.6%；次缢痕增加（包括1、9和16号染色体）9例，占6.4%；9号染色体臂间倒位24例，占17.0%；Y染色体变异10例，占7.1%。结论：染色体多态性与不良临床生殖效应有关联。
目的：研究染色體多態性與不良臨床生殖效應之間的關繫。方法：常規外週血淋巴細胞培養，製片，G、C、N顯帶，覈型分析。結果：2660例病人中檢齣染色體變異141例，其中多態性變異為58例，分彆包括D、G組短臂或隨體區延長15例，佔10.6%；次縊痕增加（包括1、9和16號染色體）9例，佔6.4%；9號染色體臂間倒位24例，佔17.0%；Y染色體變異10例，佔7.1%。結論：染色體多態性與不良臨床生殖效應有關聯。
목적：연구염색체다태성여불량림상생식효응지간적관계。방법：상규외주혈림파세포배양，제편，G、C、N현대，핵형분석。결과：2660례병인중검출염색체변이141례，기중다태성변이위58례，분별포괄D、G조단비혹수체구연장15례，점10.6%；차액흔증가（포괄1、9화16호염색체）9례，점6.4%；9호염색체비간도위24례，점17.0%；Y염색체변이10례，점7.1%。결론：염색체다태성여불량림상생식효응유관련。
Objective:To study the relationship between chromosome polymorphism and the abnormal reproductive effect. Methods:The peripheral blood lymphocytes of the patients were cultured routinely of karotype analysis with G,C and N banding. Results:There were 141 cases with chromosome variation in 2660 patients.58 cases with chromosome polymorphism,including 15 cases (10.6%) with the short arm lengthened of chromosome D/G group, 9 cases (6.4%) with the SC region lengthened of chromosome 1,9 and 16, 24 cases (17.0%) with inv(9) and 10 cases (7.1%) with Y chromosome polymorphism were observed. Conclusion: Chromosome polymorphism is related to the abnormal reproductive effect.
