CAJ | 학술논문

目的：建立药品和保健品软胶囊壳中有害元素铬的检测方法。方法采用石墨炉-原子吸收分光光度法进行测定，波长357．9 nm ，狭缝宽度为0．7 nm ，氘灯作为背景校正，微波消解对样品进行前处理。结果回归方程：Y＝0．01016 X＋0．00132，在0～50μg · L -1范围内线性关系良好（r＝0．9989），方法的检出限为0．02 mg · kg -1，定量限为0．08 mg · kg -1。高中低3个质量浓度平均回收率分别为101．4％，100．8％和99．7％，RSD分别为1．9％，2．1％和3．2％。结论该方法简便、准确、灵敏度高，适用于药品和保健品软胶囊壳中有害元素铬的含量测定。
목적：건립약품화보건품연효낭각중유해원소락적검측방법。방법채용석묵로-원자흡수분광광도법진행측정，파장357．9 nm ，협봉관도위0．7 nm ，도등작위배경교정，미파소해대양품진행전처리。결과회귀방정：Y＝0．01016 X＋0．00132，재0～50μg · L -1범위내선성관계량호（r＝0．9989），방법적검출한위0．02 mg · kg -1，정량한위0．08 mg · kg -1。고중저3개질량농도평균회수솔분별위101．4％，100．8％화99．7％，RSD분별위1．9％，2．1％화3．2％。결론해방법간편、준학、령민도고，괄용우약품화보건품연효낭각중유해원소락적함량측정。
Objective To establish a method of microwave digestion-furnace atom absorption spectrometry for the determination of chromium in soft capsule shells of drug and health food .Methods The determination conditions of microwave digestion-furnace at-om absorbance spectrometry were optimized .The content of chromium was determined under the wavelength of 357 .9 nm ,with the slit width 0 .7 nm .Results The calibration curve was linear in the range of 0-50 μg · L -1 (r=0 .998 9) ,the limit of detection was 0 .02 mg · kg -1 ,and the limit of quantification was 0 .08 mg · kg -1 .The average recoveries at three levels were 101 .4% , 100 .8% and 99 .7% ,respectively ,and the RSD were 1 .9% ,2 .1 % and 3 .2% ,respectively .Conclusion This method is simple , accurate ,and suitable for the determination of chromium in soft capsule shells of drug and health food .