CAJ | 학술논문

目的：研究单纯性肥胖患儿BM I相关危险因素，为预防肥胖相关疾病在儿童中的流行提供一定的指导。方法：对68例单纯性肥胖儿童测量身高、体重，留空腹血并检测血脂、肝功、血糖、胰岛素、C反应蛋白、单核细胞趋化因子、内脂素。结果：线性相关分析显示，BM I与C反应蛋白、单核细胞趋化因子、谷草转氨酶、甘油三酯、总胆固醇、高密度脂蛋白、低密度脂蛋白、胰岛素等具有简单线性相关；多元线性回归显示，甘油三酯、胰岛素、C反应蛋白、低密度脂蛋白与BM I密切相关。结论：甘油三酯、胰岛素、C反应蛋白、低密度脂蛋白与肥胖相关疾病密切相关，肥胖儿童通过降低其BM I水平，对于预防血脂紊乱、炎症性疾病及2型糖尿病的发生有重要意义。
목적：연구단순성비반환인BM I상관위험인소，위예방비반상관질병재인동중적류행제공일정적지도。방법：대68례단순성비반인동측량신고、체중，류공복혈병검측혈지、간공、혈당、이도소、C반응단백、단핵세포추화인자、내지소。결과：선성상관분석현시，BM I여C반응단백、단핵세포추화인자、곡초전안매、감유삼지、총담고순、고밀도지단백、저밀도지단백、이도소등구유간단선성상관；다원선성회귀현시，감유삼지、이도소、C반응단백、저밀도지단백여BM I밀절상관。결론：감유삼지、이도소、C반응단백、저밀도지단백여비반상관질병밀절상관，비반인동통과강저기BM I수평，대우예방혈지문란、염증성질병급2형당뇨병적발생유중요의의。
Objective:To study the relation between BMI and risk factors of obesity-related disease and provide some guidance for preventing of obesity-related disease prevalence in children .Method:We recruited 68 obese children and the subjects’ body weight ,height were measured according to standardized techniques .Also lip-ids ,liver function ,blood glucose ,insulin ,C-reactive protein ,monocyte chemotactic factor ,visfatin were tested . Results :The linear correlation analysis showed that BMI had a simple linear correlation with C-reactive protein , monocyte chemotactic factor ,aspartate aminotransferase ,triglycerides ,total cholesterol ,high density lipoprotein , LDL and insulin ,we analysis with multivariate linear regression and it showed that triglycerides ,insulin ,C-reactive protein ,low-density lipoprotein were closely related with BMI .Conclusion :Triglycerides ,insulin ,C-reactive pro-tein and low-density lipoprotein are closely related to obesity-related diseases .It is important for obese children re-duce the level of BMI to prevent lipid disorders ,inflammatory diseases and type 2 diabetes .