中国医院统计
中國醫院統計
중국의원통계
CHINESE JOURNAL OF HOSPITAL STATISTICS
2013年
5期
348-350
,共3页
宫颈上皮内瘤变%复发%原因%影响因素
宮頸上皮內瘤變%複髮%原因%影響因素
궁경상피내류변%복발%원인%영향인소
Cervical intraepithelial neoplasias ( CIN)%Relapse%Cause%Influencing factors
目的：探讨宫颈上皮内瘤变（ CIN）术后复发原因及其影响因素，为临床预防和治疗宫颈上皮内瘤变提供依据。方法选择我院妇产科收治的宫颈上皮内瘤变患者375例，依据宫颈上皮内瘤变是否复发分为复发组（ n＝68）和未复发组（ n＝307），比较两组各因素的差异性，并采用多因素logistic回归分析影响宫颈上皮内瘤变复发的危险因素。结果宫颈上皮内瘤变术后复发率为18．1％。影响宫颈上皮内瘤变复发的单因素分析结果显示：年龄、孕次、吸烟、绝经、颈管腺体累及、人乳头状瘤病毒（HPV）、切缘、手术方式等对宫颈上皮内瘤变复发的影响均有统计学意义（P＜0．05）。多因素分析结果显示：年龄（OR＝2．123）、吸烟（OR＝3．445）、颈管腺体累及（OR＝2．612）、人乳头状瘤病毒阳性（OR＝4.549）、切缘阳性（OR＝2．691）均为宫颈上皮内瘤变术后复发的危险因素。结论影响宫颈上皮内瘤变术后复发的原因较多，应根据患者自身情况和需求进行选择，降低患者的复发率，减少癌变，提高生存质量。
目的：探討宮頸上皮內瘤變（ CIN）術後複髮原因及其影響因素，為臨床預防和治療宮頸上皮內瘤變提供依據。方法選擇我院婦產科收治的宮頸上皮內瘤變患者375例，依據宮頸上皮內瘤變是否複髮分為複髮組（ n＝68）和未複髮組（ n＝307），比較兩組各因素的差異性，併採用多因素logistic迴歸分析影響宮頸上皮內瘤變複髮的危險因素。結果宮頸上皮內瘤變術後複髮率為18．1％。影響宮頸上皮內瘤變複髮的單因素分析結果顯示：年齡、孕次、吸煙、絕經、頸管腺體纍及、人乳頭狀瘤病毒（HPV）、切緣、手術方式等對宮頸上皮內瘤變複髮的影響均有統計學意義（P＜0．05）。多因素分析結果顯示：年齡（OR＝2．123）、吸煙（OR＝3．445）、頸管腺體纍及（OR＝2．612）、人乳頭狀瘤病毒暘性（OR＝4.549）、切緣暘性（OR＝2．691）均為宮頸上皮內瘤變術後複髮的危險因素。結論影響宮頸上皮內瘤變術後複髮的原因較多，應根據患者自身情況和需求進行選擇，降低患者的複髮率，減少癌變，提高生存質量。
목적：탐토궁경상피내류변（ CIN）술후복발원인급기영향인소，위림상예방화치료궁경상피내류변제공의거。방법선택아원부산과수치적궁경상피내류변환자375례，의거궁경상피내류변시부복발분위복발조（ n＝68）화미복발조（ n＝307），비교량조각인소적차이성，병채용다인소logistic회귀분석영향궁경상피내류변복발적위험인소。결과궁경상피내류변술후복발솔위18．1％。영향궁경상피내류변복발적단인소분석결과현시：년령、잉차、흡연、절경、경관선체루급、인유두상류병독（HPV）、절연、수술방식등대궁경상피내류변복발적영향균유통계학의의（P＜0．05）。다인소분석결과현시：년령（OR＝2．123）、흡연（OR＝3．445）、경관선체루급（OR＝2．612）、인유두상류병독양성（OR＝4.549）、절연양성（OR＝2．691）균위궁경상피내류변술후복발적위험인소。결론영향궁경상피내류변술후복발적원인교다，응근거환자자신정황화수구진행선택，강저환자적복발솔，감소암변，제고생존질량。
Objective To explore relapse cause and influencing factors of cervicalintraepithelial neoplasias ( CIN) after operation, provide basis for prevention and treatmentin clinic .Methods 375 cases of CIN in department of gynaecology and obstetrics in our hospital were chosen, and these cases were divided into relapse group (n=68) andnon -relapse group (n=307) according to whether or not relapse.Possiblefactors were compared between the two groups, and we used multiple logistic regres-sionmethod to screen risk factors.Results The relapse rate of CIN after operation was 18.1%.Single factor analysis of CIN re-plase indicated that age,pregnancy times, somking, menopause, cervical tubular gland involvement, HPV, cutting edge, opera-tion styles exist statistical significance.Multiple factors analysis result showed that age (OR=2.123), smoking (OR=3.445), cervical tubular gland involvement (OR=2.612), positive HPV (OR=4.549) and positive incisal margin(O R=2.691) were the risk factors of relapse of CIN after operation.Conclusion There were many factors affecting the relapse of CIN after opera-tion, we should choose treatment method according to patients’ own condition and requirement, to cut down relapse, grow down-wards canceration and raise quality of life.
