CAJ | 학술논문

目的：探讨预防接种异常反应发生的规律，评价疫苗的安全性，改善预防接种的服务质量，增强公众对预防接种的信心。方法：对2008～2011年吉林市疑似预防接种异常反应监测系统报告的453例接种一类疫苗后发生异常反应的病例进行统计分析。结果：453例疫苗接种异常反应病例中一般反应378例，异常反应53例，无疫苗事故；百白破无细胞疫苗报告例数最多为213例，占47．0％；≤l岁组异常反应例数为216例，占总例数的82％，2～6岁组72例，占15．9％；就医后痊愈者136例，占30．0％；好转者312例，占68．9％。结论：吉林市疾病预防控制中心自2008年使用AEFI监测系统以来，AEFI检测的敏感性明显提高，异常反应的防治效果显著。由于异常反应的发生原因是多方面的，还应从加强疫苗质量的监管、提高接种人员的培训等方面入手，进一步降低异常反应的发生率。
목적：탐토예방접충이상반응발생적규률，평개역묘적안전성，개선예방접충적복무질량，증강공음대예방접충적신심。방법：대2008～2011년길림시의사예방접충이상반응감측계통보고적453례접충일류역묘후발생이상반응적병례진행통계분석。결과：453례역묘접충이상반응병례중일반반응378례，이상반응53례，무역묘사고；백백파무세포역묘보고례수최다위213례，점47．0％；≤l세조이상반응례수위216례，점총례수적82％，2～6세조72례，점15．9％；취의후전유자136례，점30．0％；호전자312례，점68．9％。결론：길림시질병예방공제중심자2008년사용AEFI감측계통이래，AEFI검측적민감성명현제고，이상반응적방치효과현저。유우이상반응적발생원인시다방면적，환응종가강역묘질량적감관、제고접충인원적배훈등방면입수，진일보강저이상반응적발생솔。
Objective:To explore the causes of AEFI so as to find ways to reduce the AEFI incidence .Methods:Statistical analysis was conducted for the 453 cases who had adverse events following immunization from 2008 to 2011 in Jilin city.Results:378 cases were commom,abnormal reaction were 53 cases,To DPT AEFI report the first number .Among them,targets aged≤1 year accounted for 82%;Aged from 2 to 6 account for 15.9%;136 AEFIs were cured and 312 were getting better.Conclusion:The surveillance of AEFI informa-tion management system has good sensitivity in Jilin city , the AEFI monitoring sensitivity and timeliness is better .The causes for the ad-verse events are various .The quality of vaccines should be improved , training for inoculators must be strengthened , in order to reduce the incidence of the adv erse events .