中国伤残医学
中國傷殘醫學
중국상잔의학
CHINESE JOURNAL OF TRAUMA AND DISABILITY MEDICINE
2013年
9期
46-47
,共2页
彭昌伟%卢炳新%马振%赵鹏%白铁男
彭昌偉%盧炳新%馬振%趙鵬%白鐵男
팽창위%로병신%마진%조붕%백철남
肾母细胞瘤%成人%诊断%治疗
腎母細胞瘤%成人%診斷%治療
신모세포류%성인%진단%치료
Wilms'tumor%Adult%Diagnosis%Treatment
目的:探讨成人肾母细胞瘤的诊断和治疗方法。方法:回顾性分析天津医科大学第二医院7例成人肾母细胞瘤的临床资料。其中男4例,女3例,平均年龄33岁,肿瘤平均直径9 cm。结果:7例患者按照美国国家肾母细胞瘤研究组分期:Ⅰ期2例,Ⅱ期3例,Ⅲ期1例,Ⅳ期1例。7例均行根治性肾切除术,术后病理均证实为肾母细胞瘤,辅以放疗及化疗。随访时间3~72个月,中位随访时间30个月,其中1例患者失访,3例患者已经死亡,1例患者出现肿瘤复发并带瘤生存,2例患者无瘤生存,中位生存时间36个月。结论:成人肾母细胞瘤是一种比较少见的恶性肿瘤,术前确诊困难,病理检查是诊断成人肾母细胞瘤的金标准。早期诊断、手术治疗、辅以放疗和化疗等可明显提高治愈率并改善预后。
目的:探討成人腎母細胞瘤的診斷和治療方法。方法:迴顧性分析天津醫科大學第二醫院7例成人腎母細胞瘤的臨床資料。其中男4例,女3例,平均年齡33歲,腫瘤平均直徑9 cm。結果:7例患者按照美國國傢腎母細胞瘤研究組分期:Ⅰ期2例,Ⅱ期3例,Ⅲ期1例,Ⅳ期1例。7例均行根治性腎切除術,術後病理均證實為腎母細胞瘤,輔以放療及化療。隨訪時間3~72箇月,中位隨訪時間30箇月,其中1例患者失訪,3例患者已經死亡,1例患者齣現腫瘤複髮併帶瘤生存,2例患者無瘤生存,中位生存時間36箇月。結論:成人腎母細胞瘤是一種比較少見的噁性腫瘤,術前確診睏難,病理檢查是診斷成人腎母細胞瘤的金標準。早期診斷、手術治療、輔以放療和化療等可明顯提高治愈率併改善預後。
목적:탐토성인신모세포류적진단화치료방법。방법:회고성분석천진의과대학제이의원7례성인신모세포류적림상자료。기중남4례,녀3례,평균년령33세,종류평균직경9 cm。결과:7례환자안조미국국가신모세포류연구조분기:Ⅰ기2례,Ⅱ기3례,Ⅲ기1례,Ⅳ기1례。7례균행근치성신절제술,술후병리균증실위신모세포류,보이방료급화료。수방시간3~72개월,중위수방시간30개월,기중1례환자실방,3례환자이경사망,1례환자출현종류복발병대류생존,2례환자무류생존,중위생존시간36개월。결론:성인신모세포류시일충비교소견적악성종류,술전학진곤난,병리검사시진단성인신모세포류적금표준。조기진단、수술치료、보이방료화화료등가명현제고치유솔병개선예후。
Objective:To investigate the methods of diagnosis and treatment of adult Wilms tumor.Methods:Seven cases of a-dult Wilms tumor were analyzed retrospectively and discussed with review of literature.The patients,four male and three female, were aged 33 years.The size of tumors ranged from 5 to 16 cm ( mean 9cm) in diameter.Results:According to National Wilms Tumor Study ( NWTS) staging,there were four cases of stage,two cases of stageⅠ,three cases of stageⅡ,one case of stageⅢand one case of stage Ⅳ.All patients received radical nephrectomy,adjuvant radio therapy and chemotherapy postoperatively.All cases were confirmed as AWT by postoperative pathology.The range of the follow-up time was 3 to 72 months,and the median follow-up period was 30 months.One patient lost the follow up,three patients died,one patient survived with tumor recurrence,and two pa-tients survived without tumor recurrence.The median survival period was 36 months,and one patient lost the follow-up.Conclu-sion:Adult Wilms'tumor is a rare malignant tumor and is difficult to be diagnosed preoperatively .Pathological diagnostic is the standard diagnostic method.The early diagnosis and treatment including nephrectomy as early as possible and adjuvant radiotherapy and chemotherapy could improve the cure rate and prognosis.