浙江化工
浙江化工
절강화공
ZHEJIANG CHEMICAL INDUSTRY
2013年
10期
3-6
,共4页
鲍樟水%朱冰春%韦伟%魏优昌%孔小林
鮑樟水%硃冰春%韋偉%魏優昌%孔小林
포장수%주빙춘%위위%위우창%공소림
邻苯二甲酰胺%卤素%全氟异丙基苯胺%合成%杀虫活性
鄰苯二甲酰胺%滷素%全氟異丙基苯胺%閤成%殺蟲活性
린분이갑선알%서소%전불이병기분알%합성%살충활성
phthalic diamides%halogen%heptafluoroisopropyl aniline%synthesis%insecticidal activity
以4位卤素取代的邻苯二甲酸酐，2-氨基-2-甲基丙腈和全氟异丙基苯胺为起始原料，合成了14个未见文献报道的4位卤素取代的含七氟异丙基的新型邻苯二甲酰胺类化合物。通过1H NMR和ESI-MS确定了中间体和目标化合物的结构。生物活性测试表明，此类化合物对鳞翅目害虫具有非常好的杀虫活性，其中化合物5c和5n在0.8 mg/L质量浓度下对小菜蛾(Plutella xylostella)的致死率仍然达到100%。
以4位滷素取代的鄰苯二甲痠酐，2-氨基-2-甲基丙腈和全氟異丙基苯胺為起始原料，閤成瞭14箇未見文獻報道的4位滷素取代的含七氟異丙基的新型鄰苯二甲酰胺類化閤物。通過1H NMR和ESI-MS確定瞭中間體和目標化閤物的結構。生物活性測試錶明，此類化閤物對鱗翅目害蟲具有非常好的殺蟲活性，其中化閤物5c和5n在0.8 mg/L質量濃度下對小菜蛾(Plutella xylostella)的緻死率仍然達到100%。
이4위서소취대적린분이갑산항，2-안기-2-갑기병정화전불이병기분알위기시원료，합성료14개미견문헌보도적4위서소취대적함칠불이병기적신형린분이갑선알류화합물。통과1H NMR화ESI-MS학정료중간체화목표화합물적결구。생물활성측시표명，차류화합물대린시목해충구유비상호적살충활성，기중화합물5c화5n재0.8 mg/L질량농도하대소채아(Plutella xylostella)적치사솔잉연체도100%。
14 novel 4-halogan phthalic diamides containing heptafluoroisopropyl were synthesized by using substituted 4-halogan phthalic anhydride, 2-amino-2-methylpropionitrile and heptafluoroisopropyl aniline as starting materials. The structures of intermediates and target compounds were confirmed by 1H NMR and ESI-MS. The bioassays showed that these compounds possessed good insecticidal activities against lepidoptera pests. The mortality ratio of compounds 5c and 5n against Plutella xylostella were 100% at the concentration of 0.8 mg/L.
